Risk management of risk management: Combining proton pump inhibitors with low-dose aspirin

Harald Vonkeman; Inger Meek; Mart van de Laar

doi:10.2147/DHPS.S7206

Risk management of risk management: Combining proton pump inhibitors with low-dose aspirin

Harald Vonkeman^* (Corresponding Author), Inger Meek, Mart van de Laar

^*Corresponding author for this work

Research output: Contribution to journal › Review article › Academic › peer-review

3 Citations (Scopus)

67 Downloads (Pure)

Abstract

Low-dose aspirin is widely used in the primary and secondary prevention of cardiovascular events, but is associated with a range of upper gastrointestinal side effects. In this review, we summarize the rationale for low-dose aspirin therapy, quantify the risk for upper gastrointestinal side effects, identify the risk factors involved, and provide an overview of preventive strategies, thereby focusing on the rationale and clinical utility of combining proton-pump inhibitors with low-dose aspirin.

Original language	English
Pages (from-to)	191-204
Number of pages	14
Journal	Drug, Healthcare and Patient Safety
Volume	2
Issue number	1
DOIs	https://doi.org/10.2147/DHPS.S7206
Publication status	Published - 6 Oct 2010

Keywords

Clopidogrel
Gastrointestinal ulcers
H-receptor antagonists
Helicobacter pylori
Low-dose aspirin
Proton-pump inhibitors

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Risk management of risk management: Combining proton pump inhibitors with low-dose aspirin

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Keywords

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