Ruthenium oxide nanorods as potentiometric ph sensor for organs-on-chip purposes

Esther Tanumihardja* (Corresponding Author), Wouter Olthuis, Albert van den Berg

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

19 Citations (Scopus)
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A ruthenium oxide (RuOx) sensor for potentiometric pH sensing is currently being developed for organs-on-chip purposes. The sensor was fabricated from a Ru(OH)3 precursor, resulting in RuOx nanorods after heating. An open-circuit potential of the RuOx electrode showed a near-Nernstian response of −58.05 mV/pH, with good selectivity against potentially interfering ions (lithium, sulfate, chloride, and calcium ions). The preconditioned electrode (stored in liquid) had a long-term drift of −0.8 mV/h, and its response rate was less than 2 s. Sensitivity to oxygen was observed at an order of magnitude lower than other reported metal-oxide pH sensors. Together with miniaturizability, the RuOx pH sensor proves to be a suitable pH sensor for organs-on-chip studies.

Original languageEnglish
Article number2901
JournalSensors (Switzerland)
Issue number9
Publication statusPublished - 1 Sep 2018


  • Organs-on-chip
  • pH sensor
  • Potentiometric sensor
  • Ruthenium oxide
  • Lab-on-chip


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