Segmentation and determination of joint space width in foot radiographs

O. Schenk, D.M. de Muinck Keizer, H.J. Bernelot Moens, C.H. Slump

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    Joint damage in rheumatoid arthritis is frequently assessed using radiographs of hands and feet. Evaluation includes measurements of the joint space width (JSW) and detection of erosions. Current visual scoring methods are timeconsuming and subject to inter- and intra-observer variability. Automated measurement methods avoid these limitations and have been fairly successful in hand radiographs. This contribution aims at foot radiographs. Starting from an earlier proposed automated segmentation method we have developed a novel model based image analysis algorithm for JSW measurements. This method uses active appearance and active shape models to identify individual bones. The model compiles ten submodels, each representing a specific bone of the foot (metatarsals 1-5, proximal phalanges 1-5). We have performed segmentation experiments using 24 foot radiographs, randomly selected from a large database from the rheumatology department of a local hospital: 10 for training and 14 for testing. Segmentation was considered successful if the joint locations are correctly determined. Segmentation was successful in only 14%. To improve results a step-by-step analysis will be performed. We performed JSW measurements on 14 randomly selected radiographs. JSW was successfully measured in 75%, mean and standard deviation are 2.30±0.36mm. This is a first step towards automated determination of progression of RA and therapy response in feet using radiographs.

    Original languageEnglish
    Title of host publicationMedical Imaging 2016
    Subtitle of host publicationComputer-Aided Diagnosis
    EditorsGeorgia D. Tourassi, Samuel G. Armato
    Place of PublicationBellingham, WA
    ISBN (Electronic)9781510600201
    Publication statusPublished - 1 Jan 2016
    EventSPIE Medical Imaging 2016 - San Diego, United States
    Duration: 28 Feb 20162 Mar 2016

    Publication series

    NameProceedings of SPIE
    ISSN (Print)0277-786X
    NameProgress in Biomedical Optics and Imaging
    ISSN (Print)1605-7422


    ConferenceSPIE Medical Imaging 2016
    Country/TerritoryUnited States
    CitySan Diego


    • AAM
    • JSW
    • RA
    • Segmentation


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