Selected examples of high-pressure reactions in glass microreactors

Research output: Contribution to journalArticleAcademicpeer-review

40 Citations (Scopus)
1 Downloads (Pure)


Recent examples of high-pressure organic reactions in (flow) glass microreactors of micrometer dimensions are described. Different types of reactions such as Diels-Alder and nucleophilic aromatic substitution reactions performed in a capillary microreactor gave rate enhancements of 1.5–2.7 at 600 bar. Specifically designed flow glass microreactors, that withstand pressures of 140–690 bar, were used to study Diels-Alder and oxidation reactions. The use of supercritical fluids gives rise to considerable rate enhancements, while the use of a transparent microreactor allows to visualize phase transitions.
Original languageUndefined
Pages (from-to)1695-701
Number of pages7
JournalChemical engineering and technology
Issue number11
Publication statusPublished - 2009


  • Capillary microreactor
  • Miniaturization
  • IR-72778
  • Supercritical fluids
  • METIS-262774
  • Diels-Alder reaction

Cite this