Abstract
Recent examples of high-pressure organic reactions in (flow) glass microreactors of micrometer dimensions are described. Different types of reactions such as Diels-Alder and nucleophilic aromatic substitution reactions performed in a capillary microreactor gave rate enhancements of 1.5–2.7 at 600 bar. Specifically designed flow glass microreactors, that withstand pressures of 140–690 bar, were used to study Diels-Alder and oxidation reactions. The use of supercritical fluids gives rise to considerable rate enhancements, while the use of a transparent microreactor allows to visualize phase transitions.
| Original language | Undefined |
|---|---|
| Pages (from-to) | 1695-701 |
| Number of pages | 7 |
| Journal | Chemical engineering and technology |
| Volume | 32 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - 2009 |
Keywords
- Capillary microreactor
- Miniaturization
- IR-72778
- Supercritical fluids
- METIS-262774
- Diels-Alder reaction