Selected examples of high-pressure reactions in glass microreactors

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Abstract

Recent examples of high-pressure organic reactions in (flow) glass microreactors of micrometer dimensions are described. Different types of reactions such as Diels-Alder and nucleophilic aromatic substitution reactions performed in a capillary microreactor gave rate enhancements of 1.5–2.7 at 600 bar. Specifically designed flow glass microreactors, that withstand pressures of 140–690 bar, were used to study Diels-Alder and oxidation reactions. The use of supercritical fluids gives rise to considerable rate enhancements, while the use of a transparent microreactor allows to visualize phase transitions.
Original languageUndefined
Pages (from-to)1695-701
Number of pages7
JournalChemical engineering and technology
Volume32
Issue number11
DOIs
Publication statusPublished - 2009

Keywords

  • Capillary microreactor
  • Miniaturization
  • IR-72778
  • Supercritical fluids
  • METIS-262774
  • Diels-Alder reaction

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