Self-assembled carbon nanotube-DNA hybrids at the nanoscale: Morphological and conductive properties probed by atomic force microscopy

M. Santonicola, Susanna Laurenzi, Peter M. Schön

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

6 Citations (Scopus)


Our research is focused on the engineering of novel, highly sensitive and miniaturized hybrid materials from carbon nanotubes (CNTs) and DNA molecules for applications in biosensors and medical devices. These hybrid sensors allow for a high degree of miniaturization, a key factor in the design of lightweight components while maintaining the advantages of in-situ and real-time analysis capabilities. In the first phase of the sensor design process, we investigated the structural and electrical properties of the supramolecular complexes made of amide- functionalized CNTs and double-stranded DNA. The solubilization properties of the hybrid nanotubes in aqueous solutions with different concentrations of DNA were studied, and an optimal ratio of nanotubes and biomolecules to achieve a good level of dispersion was found. Complexes formed in aqueous solution from CNTs and DNA are highly stable and maintain their properties up to one month from preparation. The morphology of the CNT-DNA composites was investigated at the nanoscale level using atomic force microscopy (AFM) and electron microscopy (SEM). Results from these experiments show the strong affinity between the surface of the amide-functionalized CNTs and the DNA strands. Further, the CNT-DNA films were investigated by atomic force microscopy in the PeakForce TUNA mode to assess the suitability of this technique in determining the local conductive properties of the hybrid films.

Original languageEnglish
Title of host publicationSymposium MM - Nanotubes and Related Nanostructures - 2014
PublisherEuropean Materials Research Society (E-MRS)
Number of pages6
ISBN (Electronic)9781605116778
Publication statusPublished - 2014
Event2014 MRS Spring Meeting & Exhibit - San Francisco, United States
Duration: 21 Apr 201425 Apr 2014


Conference2014 MRS Spring Meeting & Exhibit
Country/TerritoryUnited States
CitySan Francisco


Dive into the research topics of 'Self-assembled carbon nanotube-DNA hybrids at the nanoscale: Morphological and conductive properties probed by atomic force microscopy'. Together they form a unique fingerprint.

Cite this