TY - JOUR
T1 - Self-Assembly of Proteins
T2 - Towards Supramolecular Materials
AU - Yang, Liulin
AU - Liu, Aijie
AU - Cao, Shuqin
AU - Putri, Rindia M.
AU - Jonkheijm, Pascal
AU - Cornelissen, Jeroen J.L.M.
PY - 2016
Y1 - 2016
N2 - The study of protein self-assembly has attracted great interest over the decades, due to the important role that proteins play in life. In contrast to the major achievements that have been made in the fields of DNA origami, RNA, and synthetic peptides, methods for the design of self-assembling proteins have progressed more slowly. This Concept article provides a brief overview of studies on native protein and artificial scaffold assemblies and highlights advances in designing self-assembling proteins. The discussions are focused on design strategies for self-assembling proteins, including protein fusion, chemical conjugation, supramolecular, and computational-aided de novo design.
AB - The study of protein self-assembly has attracted great interest over the decades, due to the important role that proteins play in life. In contrast to the major achievements that have been made in the fields of DNA origami, RNA, and synthetic peptides, methods for the design of self-assembling proteins have progressed more slowly. This Concept article provides a brief overview of studies on native protein and artificial scaffold assemblies and highlights advances in designing self-assembling proteins. The discussions are focused on design strategies for self-assembling proteins, including protein fusion, chemical conjugation, supramolecular, and computational-aided de novo design.
KW - 2023 OA procedure
U2 - 10.1002/chem.201601943
DO - 10.1002/chem.201601943
M3 - Article
SN - 0947-6539
VL - 22
SP - 15570
EP - 15582
JO - Chemistry : a European journal
JF - Chemistry : a European journal
IS - 44
ER -