Self-organization of the bacterial cell-division protein FtsZ in confined environments

Sonia Mellouli, Begoña Monterroso, Esra Te Brinke, Venkatachalam Chokkalingam, Germán Rivas*, Wilhelm T.S. Huck

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

26 Citations (Scopus)


We report a microfluidic approach to generate aqueous droplets in oil of different dimensionality, stabilized by a lipid monolayer, to systematically probe the polymerization of bacterial cell-division protein FtsZ into fibrous networks as a function of the concentrations of crowding agent, FtsZ, and GTP. FtsZ bundles confined in droplets were dynamic, and their distribution depended on the intrinsic properties of the system and restrictions imposed by the spatial boundaries.

Original languageEnglish
Pages (from-to)10493-10500
Number of pages8
JournalSoft matter
Issue number44
Publication statusPublished - 28 Nov 2013
Externally publishedYes


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