Shear force imaging of soft samples in liquid using a diving bell concept

M. Koopman, B.I. de Bakker, M.F. Garcia Parajo, N.F. van Hulst

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Abstract

We present a reliable and easy-to-use system, with a perfect analogy to a diving bell, to perform tuning fork based shear force microscopy o­n soft cells in liquid. Using the diving bell concept the tuning fork vibrates in air, while the tip is immersed in solution. In this way Q factors of 200 and higher in liquid are routinely obtained. The force feedback is reliable and stable over hours requiring a minimum adjustment of the set-point during imaging. With this system, tip-sample interaction forces are kept below 350 pN, enabling us to image soft dendritic cells in a buffer solution.
Original languageUndefined
Pages (from-to)5083-5085
Number of pages3
JournalApplied physics letters
Volume83
Issue number24
DOIs
Publication statusPublished - 2003

Keywords

  • IR-40692
  • METIS-213758

Cite this

Koopman, M., de Bakker, B. I., Garcia Parajo, M. F., & van Hulst, N. F. (2003). Shear force imaging of soft samples in liquid using a diving bell concept. Applied physics letters, 83(24), 5083-5085. https://doi.org/10.1063/1.1634385