Shear force imaging of soft samples in liquid using a diving bell concept

M. Koopman; B.I. de Bakker; M.F. Garcia Parajo; N.F. van Hulst

doi:10.1063/1.1634385

Shear force imaging of soft samples in liquid using a diving bell concept

M. Koopman
, B.I. de Bakker
, M.F. Garcia Parajo
, N.F. van Hulst

Optical Sciences

Research output: Contribution to journal › Article › Academic › peer-review

49 Citations (Scopus)

6 Downloads (Pure)

Abstract

We present a reliable and easy-to-use system, with a perfect analogy to a diving bell, to perform tuning fork based shear force microscopy on soft cells in liquid. Using the diving bell concept the tuning fork vibrates in air, while the tip is immersed in solution. In this way Q factors of 200 and higher in liquid are routinely obtained. The force feedback is reliable and stable over hours requiring a minimum adjustment of the set-point during imaging. With this system, tip-sample interaction forces are kept below 350 pN, enabling us to image soft dendritic cells in a buffer solution.

Original language	Undefined
Pages (from-to)	5083-5085
Number of pages	3
Journal	Applied physics letters
Volume	83
Issue number	24
DOIs	https://doi.org/10.1063/1.1634385
Publication status	Published - 2003

Keywords

IR-40692
METIS-213758

Access to Document

10.1063/1.1634385

Cite this

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abstract = "We present a reliable and easy-to-use system, with a perfect analogy to a diving bell, to perform tuning fork based shear force microscopy on soft cells in liquid. Using the diving bell concept the tuning fork vibrates in air, while the tip is immersed in solution. In this way Q factors of 200 and higher in liquid are routinely obtained. The force feedback is reliable and stable over hours requiring a minimum adjustment of the set-point during imaging. With this system, tip-sample interaction forces are kept below 350 pN, enabling us to image soft dendritic cells in a buffer solution.",

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