We demonstrate heterodyne detection of CARS signals using a cascaded phase-preserving chain to generate the CARS input wavelengths and a coherent local oscillator. The heterodyne ampli¯cation by the local oscillator re- veals a window for shot noise limited detection before the signal-to-noise is limited by amplitude °uctuations. We demonstrate an improvement in sensitivity by more than 3 orders of magnitude for detection using a photodiode. This will enable CARS microscopy to reveal concentrations below the current mMolar range.
|Publication status||Published - 2008|
|Event||SPIE San Jose: Multiphoton Microscopy in the Biomedical Sciences VIII - |
Duration: 1 Jan 1900 → …
|Conference||SPIE San Jose|
|Period||1/01/00 → …|