Simulation of multipolar fiber selective neural stimulation using intrafascicular electrodes

J.H. Meier, Jan H. Meier, Wim Rutten, Arne E. Zoutman, H.B.K. Boom, Piet Bergveld

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    Abstract

    A realistic, quantitative model for the excitation of myelinated nerve fibers by intrafascicular electrodes is presented. It predicts the stimulatory regions of any configuration of any number of electrodes, positioned anywhere inside the fascicle. The model has two parts. First, the nerve fiber is represented by a lumped electrical network and its response to an arbitrary extracellular potential field, is calculated. Second, assuming a cylindrical geometry of the nerve bundle and its surroundings, an analytical expression for this field is derived. With realistic parameters, the model is applied to two cases: monopolar stimulation by a single cathode and stimulation by a specific tripolar configuration. It is shown that tripolar stimulation has the better spatial conductivity of the medium surrounding the nerve and yields a more natural recruitment order
    Original languageUndefined
    Pages (from-to)122-134
    Number of pages13
    JournalIEEE transactions on biomedical engineering
    Volume0
    Issue number39
    DOIs
    Publication statusPublished - 1992

    Keywords

    • METIS-112207
    • IR-15332

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