Simultaneous imaging of ultrasound attenuation, speed of sound and optical absorption in a photoacoustic setup

Rene Willemink, Srirang Manohar, Jithin Jose, Cornelis H. Slump, Ferdinand van der Heijden, Ton van Leeuwen

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

    4 Citations (Scopus)

    Abstract

    Photoacoustic imaging is a relatively new medical imaging modality. In principle it can be used to image the optical absorption distribution of an object by measurements of optically induced acoustic signals. Recently we have developed a modified photoacoustic measurement system which can be used to simultaneously image the ultrasound propagation parameters as well. By proper placement of a passive element we obtain isolated measurements of the object's ultrasound propagation parameters, independent of the optical absorption inside the object. This passive element acts as a photoacoustic source and measurements are obtained by allowing the generated ultrasound signal to propagate through the object. Images of the ultrasound propagation parameters, being the attenuation and speed of sound, can then be reconstructed by inversion of a measurement model. This measurement model relates the projections non-linearly to the unknown images, due to ray refraction effects. After estimating the speed of sound and attenuation distribution, the optical absorption distribution is reconstructed. In this reconstruction problem we take into account the previously estimated speed of sound distribution. So far, the reconstruction algorithms have been tested using computer simulations. The method has been compared with existing algorithms and good results have been obtained.
    Original languageEnglish
    Title of host publicationProceedings Medical Imaging 2009: Ultrasonic Imaging and Signal Processing
    EditorsStephen A. McAleavey, Jan D'hooge
    Place of PublicationBellingham, U.S.A.
    PublisherSPIE
    ISBN (Print)9780819475169
    DOIs
    Publication statusPublished - 8 Feb 2009
    EventProceedings Medical Imaging 2009: Ultrasonic Imaging and Signal Processing - Lake Buena Vista, FL, USA
    Duration: 8 Feb 20098 Feb 2009

    Publication series

    NameProceedings of SPIE
    PublisherSPIE Digital Library
    Volume7265
    ISSN (Print)0277-786X

    Conference

    ConferenceProceedings Medical Imaging 2009: Ultrasonic Imaging and Signal Processing
    Period8/02/098/02/09
    Other8 Feb 2009

    Keywords

    • Photoacoustic imaging
    • Ultrasound tomography
    • Inhomogeneous speed of sound
    • Ray refraction correction

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