Simultaneous tracking of multiple nociceptive thresholds: a simulation and human subject study

Jan R. Buitenweg; Robert Doll; Hil Gaétan Ellart Meijer; Petrus H. Veltink

Simultaneous tracking of multiple nociceptive thresholds: a simulation and human subject study

Jan R. Buitenweg, Robert Doll, Hil Gaétan Ellart Meijer, Petrus H. Veltink

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic

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Abstract

Monte Carlo simulations were performed to compare bias, precision and bandwidth of thresh-old estimates while varying the number of simultaneous tracked thresholds (1-7). An adaptive random staircase procedure was used as stimulus selection procedure while logistic regression was used to obtain threshold estimates. We found that the bias was similar in all simulations. Moreover, precision and bandwidth lowered with more simultaneous tracked thresholds. Three different numbers of simultaneous tracked thresholds were compared in a human sub-ject study. A cold pressor was applied as nociceptive conditioning stimulus. Electrocutaneous stimulation was used for nociceptive detection threshold tracking before, during and after the conditioning stimulus.

Original language	Undefined
Title of host publication	Fourth Dutch Bio-Medical Engineering Conference 2013
Place of Publication	Egmond aan Zee
Publisher	BME
Pages	113-113
Number of pages	1
ISBN (Print)	not assigned
Publication status	Published - Jan 2013
Event	4th Dutch Bio-Medical Engineering Conference, BME 2013 - Hotel Zuiderduin, Egmond aan Zee, Netherlands Duration: 24 Jan 2013 → 25 Jan 2013 Conference number: 4 http://www.bme2013.nl/

Publication series

Name
Publisher	BME

Conference

Conference	4th Dutch Bio-Medical Engineering Conference, BME 2013
Abbreviated title	BME
Country/Territory	Netherlands
City	Egmond aan Zee
Period	24/01/13 → 25/01/13
Other	Fourth Dutch BME Conference
Internet address	http://www.bme2013.nl/

Keywords

EWI-23270
BSS-Central mechanisms underlying chronic pain
Nociception
Pain
METIS-296400
IR-85976
Monte Carlo simulations
Psychophysics
human subjects

Access to Document

http://www.bme2013.nl/program/show_slot/37

Cite this

@inproceedings{98249b39de17464385f77106126046a5,

title = "Simultaneous tracking of multiple nociceptive thresholds: a simulation and human subject study",

abstract = "Monte Carlo simulations were performed to compare bias, precision and bandwidth of thresh-old estimates while varying the number of simultaneous tracked thresholds (1-7). An adaptive random staircase procedure was used as stimulus selection procedure while logistic regression was used to obtain threshold estimates. We found that the bias was similar in all simulations. Moreover, precision and bandwidth lowered with more simultaneous tracked thresholds. Three different numbers of simultaneous tracked thresholds were compared in a human sub-ject study. A cold pressor was applied as nociceptive conditioning stimulus. Electrocutaneous stimulation was used for nociceptive detection threshold tracking before, during and after the conditioning stimulus.",

keywords = "EWI-23270, BSS-Central mechanisms underlying chronic pain, Nociception, Pain, METIS-296400, IR-85976, Monte Carlo simulations, Psychophysics, human subjects",

author = "Buitenweg, {Jan R.} and Robert Doll and Meijer, {Hil Ga{\'e}tan Ellart} and Veltink, {Petrus H.}",

year = "2013",

month = jan,

language = "Undefined",

isbn = "not assigned",

publisher = "BME",

pages = "113--113",

booktitle = "Fourth Dutch Bio-Medical Engineering Conference 2013",

note = "4th Dutch Bio-Medical Engineering Conference, BME 2013 ; Conference date: 24-01-2013 Through 25-01-2013",

url = "http://www.bme2013.nl/",

}

Buitenweg, JR, Doll, R, Meijer, HGE & Veltink, PH 2013, Simultaneous tracking of multiple nociceptive thresholds: a simulation and human subject study. in Fourth Dutch Bio-Medical Engineering Conference 2013. BME, Egmond aan Zee, pp. 113-113, 4th Dutch Bio-Medical Engineering Conference, BME 2013, Egmond aan Zee, Netherlands, 24/01/13. <http://www.bme2013.nl/program/show_slot/37>

TY - GEN

T1 - Simultaneous tracking of multiple nociceptive thresholds: a simulation and human subject study

AU - Buitenweg, Jan R.

AU - Doll, Robert

AU - Meijer, Hil Gaétan Ellart

AU - Veltink, Petrus H.

N1 - Conference code: 4

PY - 2013/1

Y1 - 2013/1

N2 - Monte Carlo simulations were performed to compare bias, precision and bandwidth of thresh-old estimates while varying the number of simultaneous tracked thresholds (1-7). An adaptive random staircase procedure was used as stimulus selection procedure while logistic regression was used to obtain threshold estimates. We found that the bias was similar in all simulations. Moreover, precision and bandwidth lowered with more simultaneous tracked thresholds. Three different numbers of simultaneous tracked thresholds were compared in a human sub-ject study. A cold pressor was applied as nociceptive conditioning stimulus. Electrocutaneous stimulation was used for nociceptive detection threshold tracking before, during and after the conditioning stimulus.

AB - Monte Carlo simulations were performed to compare bias, precision and bandwidth of thresh-old estimates while varying the number of simultaneous tracked thresholds (1-7). An adaptive random staircase procedure was used as stimulus selection procedure while logistic regression was used to obtain threshold estimates. We found that the bias was similar in all simulations. Moreover, precision and bandwidth lowered with more simultaneous tracked thresholds. Three different numbers of simultaneous tracked thresholds were compared in a human sub-ject study. A cold pressor was applied as nociceptive conditioning stimulus. Electrocutaneous stimulation was used for nociceptive detection threshold tracking before, during and after the conditioning stimulus.

KW - EWI-23270

KW - BSS-Central mechanisms underlying chronic pain

KW - Nociception

KW - Pain

KW - METIS-296400

KW - IR-85976

KW - Monte Carlo simulations

KW - Psychophysics

KW - human subjects

M3 - Conference contribution

SN - not assigned

SP - 113

EP - 113

BT - Fourth Dutch Bio-Medical Engineering Conference 2013

PB - BME

CY - Egmond aan Zee

T2 - 4th Dutch Bio-Medical Engineering Conference, BME 2013

Y2 - 24 January 2013 through 25 January 2013

ER -