Single Cell Microgel Based Modular Bioinks for Uncoupled Cellular Micro- and Macrenvironments

Tom Kamperman; S.J. Henke; Albert van den Berg; S.R. Shin; A. Tamayol; A. Khademhosseini; Hermanus Bernardus Johannes Karperien; Jeroen Christianus Hermanus Leijten

doi:10.1002/adhm.201600913

Single Cell Microgel Based Modular Bioinks for Uncoupled Cellular Micro- and Macrenvironments

Tom Kamperman, S.J. Henke, Albert van den Berg, S.R. Shin, A. Tamayol, A. Khademhosseini, Hermanus Bernardus Johannes Karperien, Jeroen Christianus Hermanus Leijten

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Abstract

Modular bioinks based on single cell microgels within distinct injectable prepolymers enable uncoupling of biomaterials' micro- and macroenvironments. These inks allow biofabrication of 3D constructs that recapitulate the multiscale modular design of native tissues with a single cell resolution. This approach represents a major step forward in endowing engineered constructs with the multifunctionality that underlies the behavior of native tissues.

Original language	English
Article number	1600913
Number of pages	9
Journal	Advanced healthcare materials
Volume	6
Issue number	3
DOIs	https://doi.org/10.1002/adhm.201600913
Publication status	Published - 14 Dec 2017

Keywords

IR-103083
METIS-321044
22/4 OA procedure

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10.1002/adhm.201600913

Kamperman-2016-SingleFinal published version, 3.31 MBLicence: Taverne

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title = "Single Cell Microgel Based Modular Bioinks for Uncoupled Cellular Micro- and Macrenvironments",

abstract = "Modular bioinks based on single cell microgels within distinct injectable prepolymers enable uncoupling of biomaterials' micro- and macroenvironments. These inks allow biofabrication of 3D constructs that recapitulate the multiscale modular design of native tissues with a single cell resolution. This approach represents a major step forward in endowing engineered constructs with the multifunctionality that underlies the behavior of native tissues.",

keywords = "IR-103083, METIS-321044, 22/4 OA procedure",

author = "Tom Kamperman and S.J. Henke and {van den Berg}, Albert and S.R. Shin and A. Tamayol and A. Khademhosseini and Karperien, {Hermanus Bernardus Johannes} and Leijten, {Jeroen Christianus Hermanus}",

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doi = "10.1002/adhm.201600913",

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T1 - Single Cell Microgel Based Modular Bioinks for Uncoupled Cellular Micro- and Macrenvironments

AU - Kamperman, Tom

AU - Henke, S.J.

AU - van den Berg, Albert

AU - Shin, S.R.

AU - Tamayol, A.

AU - Khademhosseini, A.

AU - Karperien, Hermanus Bernardus Johannes

AU - Leijten, Jeroen Christianus Hermanus

PY - 2017/12/14

Y1 - 2017/12/14

N2 - Modular bioinks based on single cell microgels within distinct injectable prepolymers enable uncoupling of biomaterials' micro- and macroenvironments. These inks allow biofabrication of 3D constructs that recapitulate the multiscale modular design of native tissues with a single cell resolution. This approach represents a major step forward in endowing engineered constructs with the multifunctionality that underlies the behavior of native tissues.

AB - Modular bioinks based on single cell microgels within distinct injectable prepolymers enable uncoupling of biomaterials' micro- and macroenvironments. These inks allow biofabrication of 3D constructs that recapitulate the multiscale modular design of native tissues with a single cell resolution. This approach represents a major step forward in endowing engineered constructs with the multifunctionality that underlies the behavior of native tissues.

KW - IR-103083

KW - METIS-321044

KW - 22/4 OA procedure

U2 - 10.1002/adhm.201600913

DO - 10.1002/adhm.201600913

M3 - Article

SN - 2192-2640

VL - 6

JO - Advanced healthcare materials

JF - Advanced healthcare materials

IS - 3

M1 - 1600913

ER -

Single Cell Microgel Based Modular Bioinks for Uncoupled Cellular Micro- and Macrenvironments

Abstract

Keywords

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