Single molecule detection on the cell membrane with Near-field Scanning Optical Microscopy

B.I. de Bakker

Research output: ThesisPhD Thesis - Research UT, graduation UT

Abstract

In this research we have developed a dedicated near- field scanning optical microscope (NSOM) for molecular biology and applied it to study the spatial organization of (fluorescently labeled) proteins at the cell surface. For the first time, protein clusters and individual molecules are resolved at the cell membrane with nanometer resolution using an optical method
LanguageUndefined
Supervisors/Advisors
  • Supervisor
  • Advisor
Award date19 Mar 2004
Place of PublicationEnschede, Netherlands
Publisher
Print ISBNs90-365-2019-3
StatePublished - 19 Mar 2004

Keywords

  • IR-41416
  • METIS-218391

Cite this

de Bakker, B. I. (2004). Single molecule detection on the cell membrane with Near-field Scanning Optical Microscopy Enschede, Netherlands: University of Twente
de Bakker, B.I.. / Single molecule detection on the cell membrane with Near-field Scanning Optical Microscopy. Enschede, Netherlands : University of Twente, 2004. 135 p.
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keywords = "IR-41416, METIS-218391",
author = "{de Bakker}, B.I.",
year = "2004",
month = "3",
day = "19",
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isbn = "90-365-2019-3",
publisher = "University of Twente",
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Single molecule detection on the cell membrane with Near-field Scanning Optical Microscopy. / de Bakker, B.I.

Enschede, Netherlands : University of Twente, 2004. 135 p.

Research output: ThesisPhD Thesis - Research UT, graduation UT

TY - THES

T1 - Single molecule detection on the cell membrane with Near-field Scanning Optical Microscopy

AU - de Bakker,B.I.

PY - 2004/3/19

Y1 - 2004/3/19

N2 - In this research we have developed a dedicated near- field scanning optical microscope (NSOM) for molecular biology and applied it to study the spatial organization of (fluorescently labeled) proteins at the cell surface. For the first time, protein clusters and individual molecules are resolved at the cell membrane with nanometer resolution using an optical method

AB - In this research we have developed a dedicated near- field scanning optical microscope (NSOM) for molecular biology and applied it to study the spatial organization of (fluorescently labeled) proteins at the cell surface. For the first time, protein clusters and individual molecules are resolved at the cell membrane with nanometer resolution using an optical method

KW - IR-41416

KW - METIS-218391

M3 - PhD Thesis - Research UT, graduation UT

SN - 90-365-2019-3

PB - University of Twente

CY - Enschede, Netherlands

ER -

de Bakker BI. Single molecule detection on the cell membrane with Near-field Scanning Optical Microscopy. Enschede, Netherlands: University of Twente, 2004. 135 p.