Small Vessel Coronary Artery Disease: Rationale for Standardized Definition and Critical Appraisal of the Literature

Jorge Sanz-Sánchez, Mauro Chiarito, Gauravpal S. Gill, Liefke C. van der Heijden, Yigal Piña, Bernardo Cortese, Fernando Alfonso, Clemens von Birgelen, Jose Luis Diez Gil, Ron Waksman, Hector M. Garcia-Garcia*

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

7 Citations (Scopus)
24 Downloads (Pure)

Abstract

Small vessel coronary artery disease (CAD) is present in 30% to 67% of patients undergoing percutaneous coronary intervention according to different series, representing an unmet clinical need in light of an increased risk of technical failure, restenosis, and need for repeated revascularization. The definition of small vessel is inconsistent across trials, and no definite cutoff value has yet been determined. The lack of consensus on the definition of small vessel CAD has contributed to the high degree of heterogeneity in the safety and efficacy of the various revascularization options. Therefore, the aim of this article is to provide a critical appraisal of existing reports and to propose a reference vessel diameter of <2.5 ​mm definition of small vessel CAD to guide future clinical trials and clinical decision-making.

Original languageEnglish
Article number100403
JournalJournal of the Society for Cardiovascular Angiography and Interventions
Volume1
Issue number5
DOIs
Publication statusPublished - 1 Sept 2022

Keywords

  • coronary artery disease
  • small vessel

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