TY - JOUR
T1 - Small Vessel Coronary Artery Disease
T2 - Rationale for Standardized Definition and Critical Appraisal of the Literature
AU - Sanz-Sánchez, Jorge
AU - Chiarito, Mauro
AU - Gill, Gauravpal S.
AU - van der Heijden, Liefke C.
AU - Piña, Yigal
AU - Cortese, Bernardo
AU - Alfonso, Fernando
AU - von Birgelen, Clemens
AU - Diez Gil, Jose Luis
AU - Waksman, Ron
AU - Garcia-Garcia, Hector M.
N1 - Funding Information:
Dr von Birgelen receives institutional grant support from Abbott Vascular, Biotronik, Boston Scientific, and Medtronic. Dr Garcia-Garcia receives institutional grant support from Biotronik, Boston Scientific, Medtronic, Abbott, Neovasc, Shockwave, Phillips, and Corflow. Drs Sanz-Sánchez, Chiarito, Gill, Piña, Cortese, Alfonso, von Birgelen, Gil, and Waksman reported no financial interests.
Publisher Copyright:
© 2022 The Author(s)
PY - 2022/9/1
Y1 - 2022/9/1
N2 - Small vessel coronary artery disease (CAD) is present in 30% to 67% of patients undergoing percutaneous coronary intervention according to different series, representing an unmet clinical need in light of an increased risk of technical failure, restenosis, and need for repeated revascularization. The definition of small vessel is inconsistent across trials, and no definite cutoff value has yet been determined. The lack of consensus on the definition of small vessel CAD has contributed to the high degree of heterogeneity in the safety and efficacy of the various revascularization options. Therefore, the aim of this article is to provide a critical appraisal of existing reports and to propose a reference vessel diameter of <2.5 mm definition of small vessel CAD to guide future clinical trials and clinical decision-making.
AB - Small vessel coronary artery disease (CAD) is present in 30% to 67% of patients undergoing percutaneous coronary intervention according to different series, representing an unmet clinical need in light of an increased risk of technical failure, restenosis, and need for repeated revascularization. The definition of small vessel is inconsistent across trials, and no definite cutoff value has yet been determined. The lack of consensus on the definition of small vessel CAD has contributed to the high degree of heterogeneity in the safety and efficacy of the various revascularization options. Therefore, the aim of this article is to provide a critical appraisal of existing reports and to propose a reference vessel diameter of <2.5 mm definition of small vessel CAD to guide future clinical trials and clinical decision-making.
KW - coronary artery disease
KW - small vessel
UR - http://www.scopus.com/inward/record.url?scp=85147156387&partnerID=8YFLogxK
U2 - 10.1016/j.jscai.2022.100403
DO - 10.1016/j.jscai.2022.100403
M3 - Review article
AN - SCOPUS:85147156387
SN - 2772-9303
VL - 1
JO - Journal of the Society for Cardiovascular Angiography and Interventions
JF - Journal of the Society for Cardiovascular Angiography and Interventions
IS - 5
M1 - 100403
ER -
