Industrial revolutions (IRs) are mostly associated with how transformations regarding the operations of an enterprise affect said enterprise’s manufacturing systems. However, the impact of these transformations exceeds the production systems themselves; rather, they affect the entire value chain, from the product design and development process (PDDP) through manufacturing and supply-chain management to marketing and disposal. As the new PDDP to a large extent defines the value chain for a company, the challenge lies in ensuring that the designed product will help the company fully benefit from the IRs. By analysing the 4th IR, the authors reveal that few publications shed light on this aspect. Consequently, the purpose of this study is to establish features and properties that will shape the PDDP throughout the 4th IR and into a smart design engineering. To accomplish this, the authors conduct a systematic review of the literature, which provides ten findings. These findings are then analysed by 11 specialists both from academia and the industry, and the findings’ relations to the 4th IR and their impact on the product development process is discussed. By establishing these findings, this paper provides a platform for the understanding of what could potentially shape smart design engineering and its design-related activities.