Smoking cessation in COPD patients: (cost-)effectiveness of the smokestoptherapy and validation of abstinence

    Research output: ThesisPhD Thesis - Research UT, graduation UT

    50 Downloads (Pure)

    Abstract

    The prescribed cut-off points for all three CO monitors generate misleading results concerning the determination of the smoking status in both populations after a 12-hour period of abstinence. For the measurement of CO over time, it can be concluded that smokers are able to deceive CO monitors by short-time abstinence, unless the cut-off points are being adjusted properly. The optimal cut-off points depend upon the goal of the study but salivary cotinine measurements outperforms the CO measurements and can therefore be considered the `gold standard¿. Cotinine measurements are relatively costly; a cost-effective validation procedure combining both tools is therefore recommended.
    Original languageEnglish
    Awarding Institution
    • University of Twente
    Supervisors/Advisors
    • Seydel, E.R., Supervisor
    • van der Palen, Job J.A.M., Co-Supervisor
    • Pieterse, Marcel E., Co-Supervisor
    Award date24 Mar 2006
    Place of PublicationEnschede
    Publisher
    Print ISBNs90-365-2315-X
    Publication statusPublished - 2006

    Keywords

    • IR-55444

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