Spa treatment for primary fibromyalgia syndrom: a combination of thalassotherapy , exercise and patient education improves symptoms and quality of life.

T.R. Zijlstra, Mart A F J van de Laar, H.J. Bernelot Moens, Erik Taal, L. Zakraoui, Johannes J. Rasker

Research output: Contribution to journalArticleAcademicpeer-review

99 Downloads (Pure)


Objectives: To study the effect of a combination of thalassotherapy, exercise and patient education in people with fibromyalgia. - Methods: Patients with fibromyalgia, selected from a rheumatology out-patient department and from members of the Dutch fibromyalgia patient association, were pre-randomized to receive either 2 weeks of treatment in a Tunisian spa resort, including thalassotherapy, supervised exercise and group education (active treatment) or treatment as usual (control treatment). Primary outcome measure was health-related quality of life, measured with the RAND-36 questionnaire. Secondary measures included the Fibromyalgia Impact Questionnaire, the McGill Pain Questionnaire, the Beck Depression Inventory, tender point score and a 6-min treadmill walk test. - Results: Fifty-eight participants receiving the active treatment reported significant improvement on RAND-36 physical and mental component summary scales. For physical health, differences from the 76 controls were statistically significant after 3 months, but not after 6 and 12 months. A similar pattern of temporary improvement was seen in the self-reported secondary measures. Tender point scores and treadmill walk tests improved more after active treatment, but did not reach significant between-group differences, except for walk tests after 12 months. - Conclusions: A combination of thalassotherapy, exercise and patient education may temporarily improve fibromyalgia symptoms and health-related quality of life.
Original languageUndefined
Pages (from-to)539-546
Issue number4 (extra)
Publication statusPublished - 2005


  • Exercise
  • Health-related quality of life
  • IR-70957
  • Thalassotherapy
  • METIS-226476
  • Fibromyalgia

Cite this