Spectral analysis and a closest tree method for genetic sequences

M.A. Steel, M.D. Hendy, L.A. Székely, P.L. Erdös

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    23 Citations (Scopus)
    48 Downloads (Pure)

    Abstract

    We describe a new method for estimating the evolutionary tree linking a collection of species from their aligned four-state genetic sequences. This method, which can be adapted to provide a branch-and-bound algorithm, is statistically consistent provided the sequences have evolved according to a standard stochastic model of nucleotide mutation. Our approach exploits a recent group-theoretic description of this model.
    Original languageEnglish
    Pages (from-to)63-67
    JournalApplied mathematics letters
    Volume5
    Issue number6
    DOIs
    Publication statusPublished - 1992

    Keywords

    • IR-57456

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