Spectral analysis and a closest tree method for genetic sequences

M.A. Steel, M.D. Hendy, L.A. Székely, P.L. Erdös

    Research output: Contribution to journalArticleAcademicpeer-review

    25 Citations (Scopus)
    73 Downloads (Pure)


    We describe a new method for estimating the evolutionary tree linking a collection of species from their aligned four-state genetic sequences. This method, which can be adapted to provide a branch-and-bound algorithm, is statistically consistent provided the sequences have evolved according to a standard stochastic model of nucleotide mutation. Our approach exploits a recent group-theoretic description of this model.
    Original languageEnglish
    Pages (from-to)63-67
    JournalApplied mathematics letters
    Issue number6
    Publication statusPublished - 1992


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