@inbook{625be86c84744df98738d629134a6241,
title = "Spectroscopic low coherence interferometry",
abstract = "Low-coherence interferometry (LCI) allows high-resolution volumetric imaging of tissue morphology and provides localized optical properties that can be related to the physiological status of tissue. This chapter discusses the combination of spatial and spectroscopic information by means of spectroscopic OCT (sOCT) and low-coherence spectroscopy (LCS). We describe the theory behind these modalities for the assessment of spatially resolved optical absorption and (back)scattering coefficient spectra. These spectra can be used for the highly localized quantification of chromophore concentrations and assessment of tissue organization on (sub)cellular scales. This leads to a wealth of potential clinical applications, ranging from neonatology for the determination of billibrubin concentrations, to oncology for the optical assessment of the aggressiveness of a cancerous lesion",
keywords = "NLA",
author = "Nienke Bosschaart and {van Leeuwen}, Ton and M.C.G. Aalders and B. Hermann and W. Drexler and D.J. Faber",
year = "2015",
doi = "10.1007/978-3-319-06419-2_37",
language = "English",
isbn = "978-3-319-06418-5",
publisher = "Springer",
pages = "1163--1187",
editor = "W. Drexler and J.G. Fujimoto",
booktitle = "Optical Coherence Tomography",
address = "Germany",
}