Spherical diffusing probes for high-peak-power copper vapor/dye laser systems

Rudolf M. Verdaasdonk; Christiaan F. Swol; Tom A. Boon

doi:10.1117/12.60942

Spherical diffusing probes for high-peak-power copper vapor/dye laser systems

Rudolf M. Verdaasdonk^*, Christiaan F. Swol, Tom A. Boon

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

1 Citation (Scopus)

8 Downloads (Pure)

Abstract

Copper vapor/dye systems are used for photodynamic therapy because they can produce several watts of light at 630 nm with high efficiency. In contrast to continuous wave argon/dye laser systems, the pulsed Cu/dye systems have a peak power 10,000 higher than the average power. Because no commercial spherical diffusing fibers guaranteed at these peak powers were available to us, we developed high power diffusers ourselves. The probes, with diameters up to 3.7 mm on 600 μm fibers, have an improved thermal behavior. The output is 50 - 60% of the laser beam input. Tested with input powers up to 6 W, no damage occurred for exposure times over 15 minutes. The isotropy of the probes varied between within 1% and 25% (sd) on average. We have successfully started photodynamic therapy in patients with carcinoma in situ in the bladder using these probes.

Original language	English
Title of host publication	Proceedings of SPIE - The International Society for Optical Engineering
Publisher	SPIE
Pages	200-204
Number of pages	5
ISBN (Print)	0819407917
DOIs	https://doi.org/10.1117/12.60942
Publication status	Published - 1 Dec 1992
Externally published	Yes
Event	Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy 1992 - Los Angeles, United States Duration: 20 Jan 1992 → 21 Jan 1992

Publication series

Name	Proceedings of SPIE - The International Society for Optical Engineering
Volume	1645
ISSN (Print)	0277-786X

Conference

Conference	Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy 1992
Country/Territory	United States
City	Los Angeles
Period	20/01/92 → 21/01/92

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10.1117/12.60942

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title = "Spherical diffusing probes for high-peak-power copper vapor/dye laser systems",

abstract = "Copper vapor/dye systems are used for photodynamic therapy because they can produce several watts of light at 630 nm with high efficiency. In contrast to continuous wave argon/dye laser systems, the pulsed Cu/dye systems have a peak power 10,000 higher than the average power. Because no commercial spherical diffusing fibers guaranteed at these peak powers were available to us, we developed high power diffusers ourselves. The probes, with diameters up to 3.7 mm on 600 μm fibers, have an improved thermal behavior. The output is 50 - 60% of the laser beam input. Tested with input powers up to 6 W, no damage occurred for exposure times over 15 minutes. The isotropy of the probes varied between within 1% and 25% (sd) on average. We have successfully started photodynamic therapy in patients with carcinoma in situ in the bladder using these probes.",

author = "Verdaasdonk, {Rudolf M.} and Swol, {Christiaan F.} and Boon, {Tom A.}",

year = "1992",

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series = "Proceedings of SPIE - The International Society for Optical Engineering",

publisher = "SPIE",

pages = "200--204",

booktitle = "Proceedings of SPIE - The International Society for Optical Engineering",

note = "Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy 1992 ; Conference date: 20-01-1992 Through 21-01-1992",

}

Verdaasdonk, RM, Swol, CF & Boon, TA 1992, Spherical diffusing probes for high-peak-power copper vapor/dye laser systems. in Proceedings of SPIE - The International Society for Optical Engineering. Proceedings of SPIE - The International Society for Optical Engineering, vol. 1645, SPIE, pp. 200-204, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy 1992, Los Angeles, California, United States, 20/01/92. https://doi.org/10.1117/12.60942

Spherical diffusing probes for high-peak-power copper vapor/dye laser systems. / Verdaasdonk, Rudolf M.; Swol, Christiaan F.; Boon, Tom A.
Proceedings of SPIE - The International Society for Optical Engineering. SPIE, 1992. p. 200-204 (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 1645).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

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T1 - Spherical diffusing probes for high-peak-power copper vapor/dye laser systems

AU - Verdaasdonk, Rudolf M.

AU - Swol, Christiaan F.

AU - Boon, Tom A.

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Y1 - 1992/12/1

N2 - Copper vapor/dye systems are used for photodynamic therapy because they can produce several watts of light at 630 nm with high efficiency. In contrast to continuous wave argon/dye laser systems, the pulsed Cu/dye systems have a peak power 10,000 higher than the average power. Because no commercial spherical diffusing fibers guaranteed at these peak powers were available to us, we developed high power diffusers ourselves. The probes, with diameters up to 3.7 mm on 600 μm fibers, have an improved thermal behavior. The output is 50 - 60% of the laser beam input. Tested with input powers up to 6 W, no damage occurred for exposure times over 15 minutes. The isotropy of the probes varied between within 1% and 25% (sd) on average. We have successfully started photodynamic therapy in patients with carcinoma in situ in the bladder using these probes.

AB - Copper vapor/dye systems are used for photodynamic therapy because they can produce several watts of light at 630 nm with high efficiency. In contrast to continuous wave argon/dye laser systems, the pulsed Cu/dye systems have a peak power 10,000 higher than the average power. Because no commercial spherical diffusing fibers guaranteed at these peak powers were available to us, we developed high power diffusers ourselves. The probes, with diameters up to 3.7 mm on 600 μm fibers, have an improved thermal behavior. The output is 50 - 60% of the laser beam input. Tested with input powers up to 6 W, no damage occurred for exposure times over 15 minutes. The isotropy of the probes varied between within 1% and 25% (sd) on average. We have successfully started photodynamic therapy in patients with carcinoma in situ in the bladder using these probes.

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Spherical diffusing probes for high-peak-power copper vapor/dye laser systems

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