Standardized, modular microfluidic building blocks for automated cell culturing systems

Anke Vollertsen*, Elsbeth Bossink, Dean de Boer, Jet Spalink, Robert Passier, Albert van den Berg, Loes Segerink, Andries van der Meer, Mathieu Odijk

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

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Abstract

We report an emerging toolkit of modular and standardized MicroFluidic Building Blocks (MFBB) to ultimately form a versatile and automated system on a Fluidic Circuit Board (FCB) for high-throughput cell culturing and screening assays. The toolkit is composed of four different MFBBs to meet a total of four different purposes: (1) a metering and mixing MFBB for upstream sample preparation, (2) a gut-on-a-chip MFBB for increased biological complexity, (3) a 64-chamber MFBB for multiplexed cell culturing, and (4) a cell-in-droplet encapsulation MFBB for downstream analysis preparation.
Original languageEnglish
Title of host publication23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences
EditorsPetra Diettrich, Emanuelle Delamarche, Andreas Hierlemann
Place of PublicationBasel, Switzerland
PublisherChemical and Biological Micro Systems Society
Pages86-87
Number of pages2
Edition23
ISBN (Electronic)978-1-7334190-0-0
Publication statusPublished - 28 Oct 2019
Event23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2019 - Congress Center Basel, Basel, Switzerland
Duration: 27 Oct 201931 Oct 2019
Conference number: 23
https://cbmsociety.org/microtas/microtas2019/

Publication series

Name
ISSN (Print)1556-5904

Conference

Conference23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2019
Abbreviated titleMicroTAS 2019
CountrySwitzerland
CityBasel
Period27/10/1931/10/19
Internet address

Keywords

  • Modular
  • Standardization
  • automation
  • Microfluidic building blocks

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  • Cite this

    Vollertsen, A., Bossink, E., de Boer, D., Spalink, J., Passier, R., van den Berg, A., ... Odijk, M. (2019). Standardized, modular microfluidic building blocks for automated cell culturing systems. In P. Diettrich, E. Delamarche, & A. Hierlemann (Eds.), 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (23 ed., pp. 86-87). Basel, Switzerland: Chemical and Biological Micro Systems Society.