Stem cells

Jojanneke Jukes, Sanne Both, Janine Post, Clemens van Blitterswijk, Marcel Karperien, Jan de Boer

    Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

    3 Citations (Scopus)

    Abstract

    This chapter defines stem cells and their properties. It identifies the major differences between embryonic and adult stem cells. Stem cells can be defined by two properties: the ability to make identical copies of themselves and the ability to form other cell types of the body. These properties are also referred to as “stemness.” Stem cells may potentially provide an unlimited supply of cells that can form any of the hundreds of specialized cells in the body. It is because of these properties that stem cells are an interesting cell source for tissue engineers. Stem cells can be divided into two main groups: embryonic and adult or somatic stem cells. Embryonic stem cells are responsible for embryonic and fetal development and growth. In the human body, adult stem cells are responsible for growth, tissue maintenance and regeneration and repair of diseased or damaged tissue. Embryonic stem cells do not exist in the body. When cells are isolated from the inner cell mass of the blastocyst, they can be massively expanded in the laboratory, while maintaining their pluripotency. Adult stem cells are undifferentiated cells, which reside in differentiated tissues.
    Original languageEnglish
    Title of host publicationTissue Engineering
    EditorsClemens A. van Blitterswijk
    Place of PublicationLonden
    PublisherAcademic Press
    Pages1–26
    ISBN (Print)978-0-12-370869-4
    DOIs
    Publication statusPublished - 2008

    Keywords

    • METIS-253650

    Fingerprint Dive into the research topics of 'Stem cells'. Together they form a unique fingerprint.

  • Cite this

    Jukes, J., Both, S., Post, J., van Blitterswijk, C., Karperien, M., & de Boer, J. (2008). Stem cells. In C. A. van Blitterswijk (Ed.), Tissue Engineering (pp. 1–26). Londen: Academic Press. https://doi.org/10.1016/B978-0-12-370869-4.00001-X