Strain imaging of the lateral collateral ligament using high frequency and conventional ultrasound imaging: An ex-vivo comparison

Kaj Gijsbertse (Corresponding Author), André Sprengers, Hamid Naghibi Beidokhti, Maartje Nillesen, Chris de Korte, Nico Verdonschot

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)
19 Downloads (Pure)

Abstract

Recent first attempts of in situ ultrasound strain imaging in collateral ligaments encountered a number of challenges and illustrated a clear need for additional studies and more thorough validation of the available strain imaging methods. Therefore, in this study we experimentally validated ultrasound strain measurements of ex vivo human lateral collateral ligaments in an axial loading condition. Moreover, the use of high frequency ultrasound (>20 MHz) for strain measurement was explored and its performance compared to conventional ultrasound. The ligaments were stretched up to 5% strain and ultrasound measurements were compared to surface strain measurements from optical digital image correlation (DIC) techniques. The results show good correlations between ultrasound based and DIC based strain measures with R2 values of 0.71 and 0.93 for high frequency and conventional ultrasound, subsequently. The performance of conventional ultrasound was significantly higher compared to high frequency ultrasound strain imaging, as the high frequency based method seemed more prone to errors. This study demonstrates that ultrasound strain imaging is feasible in ex vivo lateral collateral ligaments, which are relatively small structures. Additional studies should be designed for a more informed assessment of optimal in vivo strain measurements in collateral knee ligaments.

Original languageEnglish
Pages (from-to)233-237
Number of pages5
JournalJournal of biomechanics
Volume73
DOIs
Publication statusPublished - 17 May 2018

Fingerprint

Ankle Lateral Ligament
Ligaments
Ultrasonography
Collateral Ligaments
Ultrasonics
Imaging techniques
Strain measurement
Weight-Bearing
Knee
Surface measurement

Keywords

  • High frequency ultrasound
  • Ligament mechanics
  • Ultrasound strain imaging
  • Digital image correlation

Cite this

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title = "Strain imaging of the lateral collateral ligament using high frequency and conventional ultrasound imaging: An ex-vivo comparison",
abstract = "Recent first attempts of in situ ultrasound strain imaging in collateral ligaments encountered a number of challenges and illustrated a clear need for additional studies and more thorough validation of the available strain imaging methods. Therefore, in this study we experimentally validated ultrasound strain measurements of ex vivo human lateral collateral ligaments in an axial loading condition. Moreover, the use of high frequency ultrasound (>20 MHz) for strain measurement was explored and its performance compared to conventional ultrasound. The ligaments were stretched up to 5{\%} strain and ultrasound measurements were compared to surface strain measurements from optical digital image correlation (DIC) techniques. The results show good correlations between ultrasound based and DIC based strain measures with R2 values of 0.71 and 0.93 for high frequency and conventional ultrasound, subsequently. The performance of conventional ultrasound was significantly higher compared to high frequency ultrasound strain imaging, as the high frequency based method seemed more prone to errors. This study demonstrates that ultrasound strain imaging is feasible in ex vivo lateral collateral ligaments, which are relatively small structures. Additional studies should be designed for a more informed assessment of optimal in vivo strain measurements in collateral knee ligaments.",
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Strain imaging of the lateral collateral ligament using high frequency and conventional ultrasound imaging : An ex-vivo comparison. / Gijsbertse, Kaj (Corresponding Author); Sprengers, André; Naghibi Beidokhti, Hamid; Nillesen, Maartje; de Korte, Chris; Verdonschot, Nico.

In: Journal of biomechanics, Vol. 73, 17.05.2018, p. 233-237.

Research output: Contribution to journalArticleAcademicpeer-review

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AU - de Korte, Chris

AU - Verdonschot, Nico

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