Sub-base-pair resolution by electrophoretic separation and fluorescent detection of DNA molecules in an optofluidic chip

Hugo Hoekstra; Manfred Hammer; C. Dongre; Markus Pollnau

Sub-base-pair resolution by electrophoretic separation and fluorescent detection of DNA molecules in an optofluidic chip

Hugo Hoekstra, Manfred Hammer, C. Dongre, Markus Pollnau

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic

Abstract

Applying capillary electrophoresis, we separate and detect two sets of fluorescent-labeled DNA molecules in the 150-1000 base-pair range and achieve a sizing accuracy of 4x10^-4, enabling micro-chip analysis of single-base-pair deletion/insertion.

Original language	Undefined
Title of host publication	International Conference on Luminescence, ICL 2014
Place of Publication	Wrocław
Publisher	Institute of Low Temperature and Structure Research, Polish Academy of Sciences
Pages	Paper I-44
Number of pages	1
ISBN (Print)	not assigned
Publication status	Published - Jul 2014
Event	International Conference on Luminescence, ICL 2014 - Wrocław, Poland Duration: 13 Jul 2014 → 18 Jul 2014

Publication series

Name
Publisher	Institute of Low Temperature and Structure Research, Polish Academy of Sciences

Conference

Conference	International Conference on Luminescence, ICL 2014
Country/Territory	Poland
City	Wrocław
Period	13/07/14 → 18/07/14

Keywords

EWI-24895
IR-91430
METIS-305938
IOMS-SNS: SENSORS

Access to Document

http://eprints.eemcs.utwente.nl/secure2/24895/01/ICL14_Hoekstra.pdf

Cite this

Hoekstra, H., Hammer, M., Dongre, C., & Pollnau, M. (2014). Sub-base-pair resolution by electrophoretic separation and fluorescent detection of DNA molecules in an optofluidic chip. In International Conference on Luminescence, ICL 2014 (pp. Paper I-44). Institute of Low Temperature and Structure Research, Polish Academy of Sciences. http://eprints.eemcs.utwente.nl/secure2/24895/01/ICL14_Hoekstra.pdf

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title = "Sub-base-pair resolution by electrophoretic separation and fluorescent detection of DNA molecules in an optofluidic chip",

abstract = "Applying capillary electrophoresis, we separate and detect two sets of fluorescent-labeled DNA molecules in the 150-1000 base-pair range and achieve a sizing accuracy of 4x10^-4, enabling micro-chip analysis of single-base-pair deletion/insertion.",

keywords = "EWI-24895, IR-91430, METIS-305938, IOMS-SNS: SENSORS",

author = "Hugo Hoekstra and Manfred Hammer and C. Dongre and Markus Pollnau",

note = "Paper I-44 ; null ; Conference date: 13-07-2014 Through 18-07-2014",

year = "2014",

month = jul,

language = "Undefined",

isbn = "not assigned",

publisher = "Institute of Low Temperature and Structure Research, Polish Academy of Sciences",

pages = "Paper I--44",

booktitle = "International Conference on Luminescence, ICL 2014",

}

Hoekstra, H, Hammer, M, Dongre, C & Pollnau, M 2014, Sub-base-pair resolution by electrophoretic separation and fluorescent detection of DNA molecules in an optofluidic chip. in International Conference on Luminescence, ICL 2014. Institute of Low Temperature and Structure Research, Polish Academy of Sciences, Wrocław, pp. Paper I-44, International Conference on Luminescence, ICL 2014, Wrocław, Poland, 13/07/14. <http://eprints.eemcs.utwente.nl/secure2/24895/01/ICL14_Hoekstra.pdf>

Sub-base-pair resolution by electrophoretic separation and fluorescent detection of DNA molecules in an optofluidic chip. / Hoekstra, Hugo; Hammer, Manfred; Dongre, C. et al.

International Conference on Luminescence, ICL 2014. Wrocław : Institute of Low Temperature and Structure Research, Polish Academy of Sciences, 2014. p. Paper I-44.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic

TY - GEN

T1 - Sub-base-pair resolution by electrophoretic separation and fluorescent detection of DNA molecules in an optofluidic chip

AU - Hoekstra, Hugo

AU - Hammer, Manfred

AU - Dongre, C.

AU - Pollnau, Markus

N1 - Paper I-44

PY - 2014/7

Y1 - 2014/7

N2 - Applying capillary electrophoresis, we separate and detect two sets of fluorescent-labeled DNA molecules in the 150-1000 base-pair range and achieve a sizing accuracy of 4x10^-4, enabling micro-chip analysis of single-base-pair deletion/insertion.

AB - Applying capillary electrophoresis, we separate and detect two sets of fluorescent-labeled DNA molecules in the 150-1000 base-pair range and achieve a sizing accuracy of 4x10^-4, enabling micro-chip analysis of single-base-pair deletion/insertion.

KW - EWI-24895

KW - IR-91430

KW - METIS-305938

KW - IOMS-SNS: SENSORS

M3 - Conference contribution

SN - not assigned

SP - Paper I-44

BT - International Conference on Luminescence, ICL 2014

PB - Institute of Low Temperature and Structure Research, Polish Academy of Sciences

CY - Wrocław

Y2 - 13 July 2014 through 18 July 2014

ER -