Sub-base-pair resolution by electrophoretic separation and fluorescent detection of DNA molecules in an optofluidic chip

Hugo Hoekstra, Manfred Hammer, C. Dongre, Markus Pollnau

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

    Abstract

    Applying capillary electrophoresis, we separate and detect two sets of fluorescent-labeled DNA molecules in the 150-1000 base-pair range and achieve a sizing accuracy of 4x10^-4, enabling micro-chip analysis of single-base-pair deletion/insertion.
    Original languageUndefined
    Title of host publicationInternational Conference on Luminescence, ICL 2014
    Place of PublicationWrocław
    PublisherInstitute of Low Temperature and Structure Research, Polish Academy of Sciences
    PagesPaper I-44
    Number of pages1
    ISBN (Print)not assigned
    Publication statusPublished - Jul 2014
    EventInternational Conference on Luminescence, ICL 2014 - Wrocław, Poland
    Duration: 13 Jul 201418 Jul 2014

    Publication series

    Name
    PublisherInstitute of Low Temperature and Structure Research, Polish Academy of Sciences

    Conference

    ConferenceInternational Conference on Luminescence, ICL 2014
    CountryPoland
    CityWrocław
    Period13/07/1418/07/14

    Keywords

    • EWI-24895
    • IR-91430
    • METIS-305938
    • IOMS-SNS: SENSORS

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