Sub-base-pair resolution by electrophoretic separation and fluorescent detection of DNA molecules in an optofluidic chip

Hugo Hoekstra, Manfred Hammer, C. Dongre, Markus Pollnau

Abstract

Applying capillary electrophoresis, we separate and detect two sets of fluorescent-labeled DNA molecules in the 150-1000 base-pair range and achieve a sizing accuracy of 4x10^-4, enabling micro-chip analysis of single-base-pair deletion/insertion.
Original languageUndefined
Title of host publicationInternational Conference on Luminescence, ICL 2014
Place of PublicationWrocław
PublisherInstitute of Low Temperature and Structure Research, Polish Academy of Sciences
PagesPaper I-44
Number of pages1
ISBN (Print)not assigned
StatePublished - Jul 2014

Publication series

Name
PublisherInstitute of Low Temperature and Structure Research, Polish Academy of Sciences

Fingerprint

Genetic Conjugation
Molecules

Keywords

  • EWI-24895
  • IR-91430
  • METIS-305938
  • IOMS-SNS: SENSORS

Cite this

Hoekstra, H., Hammer, M., Dongre, C., & Pollnau, M. (2014). Sub-base-pair resolution by electrophoretic separation and fluorescent detection of DNA molecules in an optofluidic chip. In International Conference on Luminescence, ICL 2014 (pp. Paper I-44). Wrocław: Institute of Low Temperature and Structure Research, Polish Academy of Sciences.

Hoekstra, Hugo; Hammer, Manfred; Dongre, C.; Pollnau, Markus / Sub-base-pair resolution by electrophoretic separation and fluorescent detection of DNA molecules in an optofluidic chip.

International Conference on Luminescence, ICL 2014. Wrocław : Institute of Low Temperature and Structure Research, Polish Academy of Sciences, 2014. p. Paper I-44.

Research output: ScientificConference contribution

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title = "Sub-base-pair resolution by electrophoretic separation and fluorescent detection of DNA molecules in an optofluidic chip",
abstract = "Applying capillary electrophoresis, we separate and detect two sets of fluorescent-labeled DNA molecules in the 150-1000 base-pair range and achieve a sizing accuracy of 4x10^-4, enabling micro-chip analysis of single-base-pair deletion/insertion.",
keywords = "EWI-24895, IR-91430, METIS-305938, IOMS-SNS: SENSORS",
author = "Hugo Hoekstra and Manfred Hammer and C. Dongre and Markus Pollnau",
note = "Paper I-44",
year = "2014",
month = "7",
isbn = "not assigned",
publisher = "Institute of Low Temperature and Structure Research, Polish Academy of Sciences",
pages = "Paper I--44",
booktitle = "International Conference on Luminescence, ICL 2014",

}

Hoekstra, H, Hammer, M, Dongre, C & Pollnau, M 2014, Sub-base-pair resolution by electrophoretic separation and fluorescent detection of DNA molecules in an optofluidic chip. in International Conference on Luminescence, ICL 2014. Institute of Low Temperature and Structure Research, Polish Academy of Sciences, Wrocław, pp. Paper I-44.

Sub-base-pair resolution by electrophoretic separation and fluorescent detection of DNA molecules in an optofluidic chip. / Hoekstra, Hugo; Hammer, Manfred; Dongre, C.; Pollnau, Markus.

International Conference on Luminescence, ICL 2014. Wrocław : Institute of Low Temperature and Structure Research, Polish Academy of Sciences, 2014. p. Paper I-44.

Research output: ScientificConference contribution

TY - CHAP

T1 - Sub-base-pair resolution by electrophoretic separation and fluorescent detection of DNA molecules in an optofluidic chip

AU - Hoekstra,Hugo

AU - Hammer,Manfred

AU - Dongre,C.

AU - Pollnau,Markus

N1 - Paper I-44

PY - 2014/7

Y1 - 2014/7

N2 - Applying capillary electrophoresis, we separate and detect two sets of fluorescent-labeled DNA molecules in the 150-1000 base-pair range and achieve a sizing accuracy of 4x10^-4, enabling micro-chip analysis of single-base-pair deletion/insertion.

AB - Applying capillary electrophoresis, we separate and detect two sets of fluorescent-labeled DNA molecules in the 150-1000 base-pair range and achieve a sizing accuracy of 4x10^-4, enabling micro-chip analysis of single-base-pair deletion/insertion.

KW - EWI-24895

KW - IR-91430

KW - METIS-305938

KW - IOMS-SNS: SENSORS

M3 - Conference contribution

SN - not assigned

SP - Paper I-44

BT - International Conference on Luminescence, ICL 2014

PB - Institute of Low Temperature and Structure Research, Polish Academy of Sciences

ER -

Hoekstra H, Hammer M, Dongre C, Pollnau M. Sub-base-pair resolution by electrophoretic separation and fluorescent detection of DNA molecules in an optofluidic chip. In International Conference on Luminescence, ICL 2014. Wrocław: Institute of Low Temperature and Structure Research, Polish Academy of Sciences. 2014. p. Paper I-44.