Sub-base-pair resolution during DNA separation in an optofluidic chip

Markus Pollnau, Manfred Hammer, C. Dongre, Hugo Hoekstra

Abstract

Applying capillary electrophoresis, we separate and detect two sets of fluorescent-labeled DNA molecules in the 150-1000 base-pair range and achieve a sizing accuracy of 4x10^-4, thereby enabling micro-chip analysis of genetic illnesses with single-base-pair deletion/insertion.
Original languageUndefined
Title of host publication17th European Conference on Integrated Optics, ECIO 2014
Place of PublicationNice, France
PublisherCNRS - University Nice Sophia Antipolis
PagesPaper We4bR2
Number of pages2
ISBN (Print)not assigned
StatePublished - Jun 2014
Event17th European Conference on Integrated Optics and Technical Exhibition 2014 - Nice, France

Publication series

Name
PublisherCNRS - University Nice Sophia Antipolis

Conference

Conference17th European Conference on Integrated Optics and Technical Exhibition 2014
Abbreviated titleECIO 2014
CountryFrance
CityNice
Period24/06/1427/06/14

Fingerprint

Genetic Conjugation
Molecules

Keywords

  • IOMS-SNS: SENSORS
  • EWI-24839
  • METIS-304128
  • IR-91357

Cite this

Pollnau, M., Hammer, M., Dongre, C., & Hoekstra, H. (2014). Sub-base-pair resolution during DNA separation in an optofluidic chip. In 17th European Conference on Integrated Optics, ECIO 2014 (pp. Paper We4bR2). [Paper We4bR2] Nice, France: CNRS - University Nice Sophia Antipolis.

Pollnau, Markus; Hammer, Manfred; Dongre, C.; Hoekstra, Hugo / Sub-base-pair resolution during DNA separation in an optofluidic chip.

17th European Conference on Integrated Optics, ECIO 2014. Nice, France : CNRS - University Nice Sophia Antipolis, 2014. p. Paper We4bR2 Paper We4bR2.

Research output: ScientificConference contribution

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title = "Sub-base-pair resolution during DNA separation in an optofluidic chip",
abstract = "Applying capillary electrophoresis, we separate and detect two sets of fluorescent-labeled DNA molecules in the 150-1000 base-pair range and achieve a sizing accuracy of 4x10^-4, thereby enabling micro-chip analysis of genetic illnesses with single-base-pair deletion/insertion.",
keywords = "IOMS-SNS: SENSORS, EWI-24839, METIS-304128, IR-91357",
author = "Markus Pollnau and Manfred Hammer and C. Dongre and Hugo Hoekstra",
note = "Paper We4bR2",
year = "2014",
month = "6",
isbn = "not assigned",
publisher = "CNRS - University Nice Sophia Antipolis",
pages = "Paper We4bR2",
booktitle = "17th European Conference on Integrated Optics, ECIO 2014",

}

Pollnau, M, Hammer, M, Dongre, C & Hoekstra, H 2014, Sub-base-pair resolution during DNA separation in an optofluidic chip. in 17th European Conference on Integrated Optics, ECIO 2014., Paper We4bR2, CNRS - University Nice Sophia Antipolis, Nice, France, pp. Paper We4bR2, 17th European Conference on Integrated Optics and Technical Exhibition 2014, Nice, France, 24-27 June.

Sub-base-pair resolution during DNA separation in an optofluidic chip. / Pollnau, Markus; Hammer, Manfred; Dongre, C.; Hoekstra, Hugo.

17th European Conference on Integrated Optics, ECIO 2014. Nice, France : CNRS - University Nice Sophia Antipolis, 2014. p. Paper We4bR2 Paper We4bR2.

Research output: ScientificConference contribution

TY - CHAP

T1 - Sub-base-pair resolution during DNA separation in an optofluidic chip

AU - Pollnau,Markus

AU - Hammer,Manfred

AU - Dongre,C.

AU - Hoekstra,Hugo

N1 - Paper We4bR2

PY - 2014/6

Y1 - 2014/6

N2 - Applying capillary electrophoresis, we separate and detect two sets of fluorescent-labeled DNA molecules in the 150-1000 base-pair range and achieve a sizing accuracy of 4x10^-4, thereby enabling micro-chip analysis of genetic illnesses with single-base-pair deletion/insertion.

AB - Applying capillary electrophoresis, we separate and detect two sets of fluorescent-labeled DNA molecules in the 150-1000 base-pair range and achieve a sizing accuracy of 4x10^-4, thereby enabling micro-chip analysis of genetic illnesses with single-base-pair deletion/insertion.

KW - IOMS-SNS: SENSORS

KW - EWI-24839

KW - METIS-304128

KW - IR-91357

M3 - Conference contribution

SN - not assigned

SP - Paper We4bR2

BT - 17th European Conference on Integrated Optics, ECIO 2014

PB - CNRS - University Nice Sophia Antipolis

ER -

Pollnau M, Hammer M, Dongre C, Hoekstra H. Sub-base-pair resolution during DNA separation in an optofluidic chip. In 17th European Conference on Integrated Optics, ECIO 2014. Nice, France: CNRS - University Nice Sophia Antipolis. 2014. p. Paper We4bR2. Paper We4bR2.