Sub-base-pair resolution during DNA separation in an optofluidic chip

Markus Pollnau, Manfred Hammer, C. Dongre, Hugo Hoekstra

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

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    Abstract

    Applying capillary electrophoresis, we separate and detect two sets of fluorescent-labeled DNA molecules in the 150-1000 base-pair range and achieve a sizing accuracy of 4x10^-4, thereby enabling micro-chip analysis of genetic illnesses with single-base-pair deletion/insertion.
    Original languageUndefined
    Title of host publication17th European Conference on Integrated Optics, ECIO 2014
    Place of PublicationNice, France
    PublisherCNRS - University Nice Sophia Antipolis
    PagesPaper We4bR2
    Number of pages2
    ISBN (Print)not assigned
    Publication statusPublished - Jun 2014
    Event17th European Conference on Integrated Optics and Technical Exhibition 2014 - Université Nice, Campus Saint Jean d’Angély, Nice, France
    Duration: 24 Jun 201427 Jun 2014
    Conference number: 17

    Publication series

    Name
    PublisherCNRS - University Nice Sophia Antipolis

    Conference

    Conference17th European Conference on Integrated Optics and Technical Exhibition 2014
    Abbreviated titleECIO 2014
    CountryFrance
    CityNice
    Period24/06/1427/06/14

    Keywords

    • IOMS-SNS: SENSORS
    • EWI-24839
    • METIS-304128
    • IR-91357

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