Sub-base-pair resolution during DNA separation in an optofluidic chip

Markus Pollnau; Manfred Hammer; C. Dongre; Hugo Hoekstra

Sub-base-pair resolution during DNA separation in an optofluidic chip

Markus Pollnau
, Manfred Hammer
, C. Dongre
, Hugo Hoekstra

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic

60 Downloads (Pure)

Abstract

Applying capillary electrophoresis, we separate and detect two sets of fluorescent-labeled DNA molecules in the 150-1000 base-pair range and achieve a sizing accuracy of 4x10^-4, thereby enabling micro-chip analysis of genetic illnesses with single-base-pair deletion/insertion.

Original language	Undefined
Title of host publication	17th European Conference on Integrated Optics, ECIO 2014
Place of Publication	Nice, France
Publisher	CNRS - University Nice Sophia Antipolis
Pages	Paper We4bR2
Number of pages	2
ISBN (Print)	not assigned
Publication status	Published - Jun 2014
Event	17th European Conference on Integrated Optics and Technical Exhibition 2014 - Université Nice, Campus Saint Jean d’Angély, Nice, France Duration: 24 Jun 2014 → 27 Jun 2014 Conference number: 17

Publication series

Name
Publisher	CNRS - University Nice Sophia Antipolis

Conference

Conference	17th European Conference on Integrated Optics and Technical Exhibition 2014
Abbreviated title	ECIO 2014
Country/Territory	France
City	Nice
Period	24/06/14 → 27/06/14

Keywords

IOMS-SNS: SENSORS
EWI-24839
METIS-304128
IR-91357

Access to Document

ECIO14_Pollnau

http://eprints.eemcs.utwente.nl/secure2/24839/01/ECIO14_Pollnau.pdf

Cite this

@inproceedings{7334d3e81d774bdaa9f05bacd2b1f576,

title = "Sub-base-pair resolution during DNA separation in an optofluidic chip",

abstract = "Applying capillary electrophoresis, we separate and detect two sets of fluorescent-labeled DNA molecules in the 150-1000 base-pair range and achieve a sizing accuracy of 4x10\textasciicircum{}-4, thereby enabling micro-chip analysis of genetic illnesses with single-base-pair deletion/insertion.",

keywords = "IOMS-SNS: SENSORS, EWI-24839, METIS-304128, IR-91357",

author = "Markus Pollnau and Manfred Hammer and C. Dongre and Hugo Hoekstra",

note = "Paper We4bR2 ; 17th European Conference on Integrated Optics and Technical Exhibition 2014 ; Conference date: 24-06-2014 Through 27-06-2014",

year = "2014",

month = jun,

language = "Undefined",

isbn = "not assigned",

publisher = "CNRS - University Nice Sophia Antipolis",

pages = "Paper We4bR2",

booktitle = "17th European Conference on Integrated Optics, ECIO 2014",

}

Pollnau, M, Hammer, M, Dongre, C & Hoekstra, H 2014, Sub-base-pair resolution during DNA separation in an optofluidic chip. in 17th European Conference on Integrated Optics, ECIO 2014., Paper We4bR2, CNRS - University Nice Sophia Antipolis, Nice, France, pp. Paper We4bR2, 17th European Conference on Integrated Optics and Technical Exhibition 2014, Nice, France, 24/06/14. <http://eprints.eemcs.utwente.nl/secure2/24839/01/ECIO14_Pollnau.pdf>

Sub-base-pair resolution during DNA separation in an optofluidic chip. / Pollnau, Markus; Hammer, Manfred; Dongre, C. et al.
17th European Conference on Integrated Optics, ECIO 2014. Nice, France: CNRS - University Nice Sophia Antipolis, 2014. p. Paper We4bR2 Paper We4bR2.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic

TY - GEN

T1 - Sub-base-pair resolution during DNA separation in an optofluidic chip

AU - Pollnau, Markus

AU - Hammer, Manfred

AU - Dongre, C.

AU - Hoekstra, Hugo

N1 - Conference code: 17

PY - 2014/6

Y1 - 2014/6

N2 - Applying capillary electrophoresis, we separate and detect two sets of fluorescent-labeled DNA molecules in the 150-1000 base-pair range and achieve a sizing accuracy of 4x10^-4, thereby enabling micro-chip analysis of genetic illnesses with single-base-pair deletion/insertion.

AB - Applying capillary electrophoresis, we separate and detect two sets of fluorescent-labeled DNA molecules in the 150-1000 base-pair range and achieve a sizing accuracy of 4x10^-4, thereby enabling micro-chip analysis of genetic illnesses with single-base-pair deletion/insertion.

KW - IOMS-SNS: SENSORS

KW - EWI-24839

KW - METIS-304128

KW - IR-91357

M3 - Conference contribution

SN - not assigned

SP - Paper We4bR2

BT - 17th European Conference on Integrated Optics, ECIO 2014

PB - CNRS - University Nice Sophia Antipolis

CY - Nice, France

T2 - 17th European Conference on Integrated Optics and Technical Exhibition 2014

Y2 - 24 June 2014 through 27 June 2014

ER -