Several methods have been developed to modify the surfaces of materials used in artificial hearts and circulatory assist devices to suppress the host response, especially with respect to the occurrence of clotting, cellular damage, and infections. In this review, special attention is paid to strategies for the design of non-thrombogenic surfaces, the functionalization of surfaces, the interaction of heparinized surfaces with blood components, and the occurrence of infections.
|Title of host publication||Heart Replacement|
|Subtitle of host publication||Artificial Heart 5|
|Editors||Tetsuzo Akutsu, Hitoshi Koyanagi|
|Place of Publication||Tokyo|
|Number of pages||15|
|Publication status||Published - 1996|