Abstract
The influence of neuron-adhesive pattern geometry on long-term survival of cortical neural tissue (rat brain) was studied over a time period of 15 days. Microwells (depth 0.5 /spl mu/m) with diameters of 25, 50, 100 and 150 /spl mu/m and inter-microwell distances of 15, 30, 60 and 90 /spl mu/m, were etched in a neuron-repellent fluorocarbon (FC)-layer and coated with neuron-adhesive polyethylenimine (PEI). Results showed that the survival of neural tissue was geometry-independent after 1, 4 and 8 days but was favored on 150 /spl mu/m wells after 15 days.
| Original language | Undefined |
|---|---|
| Title of host publication | Proceedings 23rd International Conference of the IEEE Engineering in Medicine and Biology Society, Isyanbul, Turkey |
| Place of Publication | Piscattaway, USA |
| Publisher | IEEE |
| Pages | - |
| Number of pages | 4 |
| ISBN (Print) | 0-7803-7213-1 |
| Publication status | Published - 25 Oct 2001 |
| Event | 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2001 - Istanbul, Turkey Duration: 25 Oct 2001 → 28 Oct 2001 Conference number: 23 |
Publication series
| Name | |
|---|---|
| Publisher | IEEE |
| Volume | 1 |
Conference
| Conference | 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2001 |
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| Abbreviated title | EMBC |
| Country/Territory | Turkey |
| City | Istanbul |
| Period | 25/10/01 → 28/10/01 |
Keywords
- METIS-200709
- IR-42182