Synthesis and binding properties of novel cyclodextrin dimers

Fokke Venema, Chantal M. Baselier, Erik van Dienst, Bianca H.M. Ruel, Martinus C. Feiters, Johannes F.J. Engbersen, David Reinhoudt, Roeland J.M. Nolte

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Abstract

The synthesis of three cyclodextrin dimers from the novel building block 3-amino-3-deoxy-heptakis(6-O-tert-butyldimethylsilyl)-ß-cyclodextrin is reported. The cyclodextrins are linked with an amide bond on their secondary sides to an ethylene, octamethylene, or a metal binding bipyridyl group. Complexation studies with the substrate 6-(p-toluidino)-2-naphthalenesulfonic acid are presented and discussed.
Original languageUndefined
Pages (from-to)1773-1776
JournalTetrahedron letters
Volume35
Issue number11
DOIs
Publication statusPublished - 1994

Keywords

  • IR-57381

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