Abstract
A new strategy for the synthesis of molecular cavities was developed by the covalent linkage of relatively rigid macrocydes (calix[4]- and
resorcin[4]arenes) which themselves possess a permanent cavity. The stepwise coupling of the respective building blocks gives carceplexes
(host-guest compounds) which have trapped guest molecules in their interior. These carceplexes exhibit a novel type of stereoisomerism
(carceroisomerism) as a result of different orientations of the guest molecules inside the cavity. The convergent, cyclic combination of two calix[4]- and two resorcin[4]arene building blocks gives a large artifical receptor molecule (holand). The holand contains a permanent cavity of nanosize dimensions which is extremely rigid for its size.
resorcin[4]arenes) which themselves possess a permanent cavity. The stepwise coupling of the respective building blocks gives carceplexes
(host-guest compounds) which have trapped guest molecules in their interior. These carceplexes exhibit a novel type of stereoisomerism
(carceroisomerism) as a result of different orientations of the guest molecules inside the cavity. The convergent, cyclic combination of two calix[4]- and two resorcin[4]arene building blocks gives a large artifical receptor molecule (holand). The holand contains a permanent cavity of nanosize dimensions which is extremely rigid for its size.
| Translated title of the contribution | Synthetic molecular cavities |
|---|---|
| Original language | German |
| Pages (from-to) | 640-642 |
| Journal | GIT |
| Volume | 40 |
| Issue number | 6 |
| Publication status | Published - 1996 |