Abstract
During biopsies, breast tissue is subjected to displacement upon needle indentation, puncture, and penetration. Thus, accurate needle placement requires pre-operative predictions of the target motions. In this paper, we used ultrasound elastography measurements to non-invasively predict elastic properties of breast tissue phantoms. These properties were used in finite element (FE) models of indentation of breast soft tissue phantoms. To validate the model predictions of target motion, experimental measurements were carried out. Breast tissue phantoms with cubic and hemispherical geometries were manufactured and included materials with different elastic properties to represent skin, adipose tissue, and lesions. Ultrasound was used to track the displacement of the target (i.e., the simulated lesion) during indentation. The FE model predictions were compared with ultrasound measurements for cases with different boundary conditions and phantom geometry. Maximum errors between measured and predicted target motions were 12% and 3% for the fully supported and partially supported cubic phantoms at 6.0 mm indentation, respectively. Further, FE-based parameter sensitivity analysis indicated that increasing skin elastic modulus and reducing the target depth location increased the target motion. Our results indicate that with a priori knowledge about the geometry, boundary conditions, and linear elastic properties, indentation of breast tissue phantoms can be accurately predicted with FE models. FE models for pre-operative planning in combination with robotic needle insertions, could play a key role in improving lesion targeting for breast biopsies.
Original language | English |
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Title of host publication | 33rd Annual International Conference of the IEEE EMBC |
Subtitle of host publication | Boston, Massachusetts USA, August 30 - September 3, 2011 |
Place of Publication | Piscataway, NJ |
Publisher | IEEE |
Pages | 5380-5385 |
Number of pages | 6 |
DOIs | |
Publication status | Published - Aug 2011 |
Event | 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2011 - Boston Marriott Copley Place Hotel, Boston, United States Duration: 30 Aug 2011 → 3 Sept 2011 Conference number: 33 |
Publication series
Name | Annual International Conference of the IEEE EMBS |
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Publisher | IEEE Engineering in Medicine & Biology Society |
Number | 33 |
ISSN (Print) | 1557-170X |
Conference
Conference | 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2011 |
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Abbreviated title | EMBC |
Country/Territory | United States |
City | Boston |
Period | 30/08/11 → 3/09/11 |