Temperature-driven self-actuated microvalve for PCR

Toyohiro Naito, Rerngchai Arayanarakool, Noritada Kaji, Yukihiro Okamoto, Manubu Tokeshi, Severine le Gac, Albert van den Berg, Y. Baba

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

    Abstract

    We report here a novel chamber-sealing valve that is self-actuated by pressure change during the cyclic temperature changes in PCR processes. Actuation of our valve requirs only a heating device employed for PCR. An UV-curable polymer is used as a device material and it allowed us to realize temperature-driven valve actuation as well as to fabricate a 3D device. The self-actuated microvalve achieves the effective sealing of microchamber for PCR even at 90ºC, which is essential to develop highly parallel PCR array device without any complicated actuator circuits.
    Original languageUndefined
    Title of host publication15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, μTAS 2011
    Place of PublicationWashington
    PublisherChemical and Biological Micro Systems Society
    Pages248-250
    Number of pages3
    ISBN (Print)978-0-979-8064-4-5
    Publication statusPublished - 2 Oct 2011
    Event15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2011 - Seattle, United States
    Duration: 2 Oct 20116 Oct 2011
    Conference number: 15
    https://microtasconferences.org/microtas2011/

    Publication series

    Name
    PublisherChemical and Biological Microsystems Society
    ISSN (Print)1556-5904

    Conference

    Conference15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2011
    Abbreviated titleMicroTAS
    CountryUnited States
    CitySeattle
    Period2/10/116/10/11
    Internet address

    Keywords

    • METIS-281592
    • EWI-20889
    • IR-78654

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