Temperature-driven self-actuated microvalve for PCR

Toyohiro Naito; Rerngchai Arayanarakool; Noritada Kaji; Yukihiro Okamoto; Manubu Tokeshi; Severine le Gac; Albert van den Berg; Y. Baba

Temperature-driven self-actuated microvalve for PCR

Toyohiro Naito, Rerngchai Arayanarakool, Noritada Kaji, Yukihiro Okamoto, Manubu Tokeshi, Severine le Gac, Albert van den Berg, Y. Baba

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

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Abstract

We report here a novel chamber-sealing valve that is self-actuated by pressure change during the cyclic temperature changes in PCR processes. Actuation of our valve requirs only a heating device employed for PCR. An UV-curable polymer is used as a device material and it allowed us to realize temperature-driven valve actuation as well as to fabricate a 3D device. The self-actuated microvalve achieves the effective sealing of microchamber for PCR even at 90ºC, which is essential to develop highly parallel PCR array device without any complicated actuator circuits.

Original language	Undefined
Title of host publication	15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, μTAS 2011
Place of Publication	Washington
Publisher	The Chemical and Biological Microsystems Society
Pages	248-250
Number of pages	3
ISBN (Print)	978-0-979-8064-4-5
Publication status	Published - 2 Oct 2011
Event	15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2011 - Seattle, United States Duration: 2 Oct 2011 → 6 Oct 2011 Conference number: 15 https://microtasconferences.org/microtas2011/

Publication series

Name
Publisher	Chemical and Biological Microsystems Society
ISSN (Print)	1556-5904

Conference

Conference	15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2011
Abbreviated title	MicroTAS
Country/Territory	United States
City	Seattle
Period	2/10/11 → 6/10/11
Internet address	https://microtasconferences.org/microtas2011/

Keywords

METIS-281592
EWI-20889
IR-78654

Access to Document

http://eprints.eemcs.utwente.nl/secure2/20889/01/084_0446.pdf

Cite this

Naito, T., Arayanarakool, R., Kaji, N., Okamoto, Y., Tokeshi, M., le Gac, S., van den Berg, A., & Baba, Y. (2011). Temperature-driven self-actuated microvalve for PCR. In 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, μTAS 2011 (pp. 248-250). The Chemical and Biological Microsystems Society. http://eprints.eemcs.utwente.nl/secure2/20889/01/084_0446.pdf

@inproceedings{788f1f75b21b43a682d29041e1952656,

title = "Temperature-driven self-actuated microvalve for PCR",

abstract = "We report here a novel chamber-sealing valve that is self-actuated by pressure change during the cyclic temperature changes in PCR processes. Actuation of our valve requirs only a heating device employed for PCR. An UV-curable polymer is used as a device material and it allowed us to realize temperature-driven valve actuation as well as to fabricate a 3D device. The self-actuated microvalve achieves the effective sealing of microchamber for PCR even at 90ºC, which is essential to develop highly parallel PCR array device without any complicated actuator circuits.",

keywords = "METIS-281592, EWI-20889, IR-78654",

author = "Toyohiro Naito and Rerngchai Arayanarakool and Noritada Kaji and Yukihiro Okamoto and Manubu Tokeshi and {le Gac}, Severine and {van den Berg}, Albert and Y. Baba",

year = "2011",

month = oct,

day = "2",

language = "Undefined",

isbn = "978-0-979-8064-4-5",

publisher = "The Chemical and Biological Microsystems Society",

pages = "248--250",

booktitle = "15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, μTAS 2011",

note = "15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2011 ; Conference date: 02-10-2011 Through 06-10-2011",

url = "https://microtasconferences.org/microtas2011/",

}

Naito, T, Arayanarakool, R, Kaji, N, Okamoto, Y, Tokeshi, M, le Gac, S , van den Berg, A & Baba, Y 2011, Temperature-driven self-actuated microvalve for PCR. in 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, μTAS 2011. The Chemical and Biological Microsystems Society, Washington, pp. 248-250, 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2011, Seattle, Washington, United States, 2/10/11. <http://eprints.eemcs.utwente.nl/secure2/20889/01/084_0446.pdf>

Temperature-driven self-actuated microvalve for PCR. / Naito, Toyohiro; Arayanarakool, Rerngchai; Kaji, Noritada et al.
15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, μTAS 2011. Washington: The Chemical and Biological Microsystems Society, 2011. p. 248-250.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

TY - GEN

T1 - Temperature-driven self-actuated microvalve for PCR

AU - Naito, Toyohiro

AU - Arayanarakool, Rerngchai

AU - Kaji, Noritada

AU - Okamoto, Yukihiro

AU - Tokeshi, Manubu

AU - le Gac, Severine

AU - van den Berg, Albert

AU - Baba, Y.

N1 - Conference code: 15

PY - 2011/10/2

Y1 - 2011/10/2

N2 - We report here a novel chamber-sealing valve that is self-actuated by pressure change during the cyclic temperature changes in PCR processes. Actuation of our valve requirs only a heating device employed for PCR. An UV-curable polymer is used as a device material and it allowed us to realize temperature-driven valve actuation as well as to fabricate a 3D device. The self-actuated microvalve achieves the effective sealing of microchamber for PCR even at 90ºC, which is essential to develop highly parallel PCR array device without any complicated actuator circuits.

AB - We report here a novel chamber-sealing valve that is self-actuated by pressure change during the cyclic temperature changes in PCR processes. Actuation of our valve requirs only a heating device employed for PCR. An UV-curable polymer is used as a device material and it allowed us to realize temperature-driven valve actuation as well as to fabricate a 3D device. The self-actuated microvalve achieves the effective sealing of microchamber for PCR even at 90ºC, which is essential to develop highly parallel PCR array device without any complicated actuator circuits.

KW - METIS-281592

KW - EWI-20889

KW - IR-78654

M3 - Conference contribution

SN - 978-0-979-8064-4-5

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EP - 250

BT - 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, μTAS 2011

PB - The Chemical and Biological Microsystems Society

CY - Washington

T2 - 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2011

Y2 - 2 October 2011 through 6 October 2011

ER -