TGV-based flow estimation for 4D leukocyte transmigration

L. Frerking, M. Burger, D. Vestweber, Christoph Brune

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    Abstract

    The aim of this paper is to track transmigrating leukocytes via TGV flow estimation. Recent results have shown the advantages of the nonlinear and higher order terms of TGV regularizers, especially in static models for denoising and medical reconstruction. We present TGV-based models for flow estimation with the goal to get an exact recovery of simple intracellular and extracellular flows, as well as its implication on realistic tracking situations for transmigration through barriers. To study and quantify different pathways of transmigrating leukocytes, we use large scale 4D fluorescence live microscopy data in vivo.
    Original languageUndefined
    Title of host publicationProceedings of the Inverse Problems from Theory to Applications Conference (IPTA)
    EditorsAlfred K. Louis, Simon Arridge, Bill Rundell
    Place of PublicationBristol
    PublisherIOP
    Pages79-83
    Number of pages5
    ISBN (Print)978-0-7503-1106-9
    Publication statusPublished - 26 Aug 2014

    Publication series

    Name
    PublisherIOP Publishing

    Keywords

    • EWI-25603
    • Transmigration
    • Tracking
    • METIS-309835
    • Optical Flow
    • Leukocytes
    • IR-94107
    • TGV

    Cite this

    Frerking, L., Burger, M., Vestweber, D., & Brune, C. (2014). TGV-based flow estimation for 4D leukocyte transmigration. In A. K. Louis, S. Arridge, & B. Rundell (Eds.), Proceedings of the Inverse Problems from Theory to Applications Conference (IPTA) (pp. 79-83). Bristol: IOP.