The influence of Cellular Interactions in Tissue Engineering for Cartilage Repair

Tissues are complex 3-dimensional structures with a highly organized architecture made up of cells and matrix. The cells and matrix in a tissue are continuously interacting with each other and (cells from) their surrounding tissues to maintain their form and function. Interactions of cells with their surrounding cells and matrix are equally important for a successful repair reaction. While in tissue engineering significant progress has been made, still a number of challenges need to be overcome for the development of clinically applicable treatments.