TY - JOUR
T1 - The initial systolic time interval in patients with spinal cord injury measured with impedance cardiography
AU - Hoekstra, Femke
AU - Martinsen, Orjan G.
AU - Verdaasdonk, Rudolf M.
AU - Janssen, Thomas W.J.
AU - Meijer, Jan H.
N1 - Conference code: 1
PY - 2012/1/1
Y1 - 2012/1/1
N2 - The Initial Systolic Time Interval (ISTI), obtained from the electrocardiogram and impedance cardiogram, is considered to be a measure for the time delay between the electrical and mechanical activity of the heart. This time delay is influenced by the sympathetic nerve system. Therefore, an observational study was performed in a group of patients (SCI) with spinal cord injuries. The relationship between the ISTI and the total heart cycle (RR-interval) was established by varying the RR-interval using an exercise stimulus to increase the heart rate. The slope of this relationship was observed to be significantly higher in the SCI-group as compared with a control group, although there was no difference in ISTI in the range of common heart rates during the test between the groups. This slope and the ISTI was observed to be significantly different in an acute patient having a recent spinal cord injury at a high level. Because of the variety in injury levels and incompleteness of the injuries further, more specific research is necessary to draw decisive conclusions with respect to the contribution of autonomic nervous control on the ISTI in SCI, although the present observations are notable.
AB - The Initial Systolic Time Interval (ISTI), obtained from the electrocardiogram and impedance cardiogram, is considered to be a measure for the time delay between the electrical and mechanical activity of the heart. This time delay is influenced by the sympathetic nerve system. Therefore, an observational study was performed in a group of patients (SCI) with spinal cord injuries. The relationship between the ISTI and the total heart cycle (RR-interval) was established by varying the RR-interval using an exercise stimulus to increase the heart rate. The slope of this relationship was observed to be significantly higher in the SCI-group as compared with a control group, although there was no difference in ISTI in the range of common heart rates during the test between the groups. This slope and the ISTI was observed to be significantly different in an acute patient having a recent spinal cord injury at a high level. Because of the variety in injury levels and incompleteness of the injuries further, more specific research is necessary to draw decisive conclusions with respect to the contribution of autonomic nervous control on the ISTI in SCI, although the present observations are notable.
UR - http://www.scopus.com/inward/record.url?scp=84874050758&partnerID=8YFLogxK
U2 - 10.1088/1742-6596/407/1/012025
DO - 10.1088/1742-6596/407/1/012025
M3 - Conference article
AN - SCOPUS:84874050758
VL - 407
JO - Journal of physics: Conference series
JF - Journal of physics: Conference series
SN - 1742-6588
IS - 1
M1 - 012025
T2 - 1st Latin-American Conference on Bioimpedance, CLABIO 2012
Y2 - 6 November 2012 through 9 November 2012
ER -