The interplay between COPD and chronic heart failure deterioration

Research output: Contribution to journalMeeting AbstractAcademic

Abstract

Background: COPD and chronic heart failure (CHF) commonly co-exist and share symptoms, which complicates disease management. It is unclear how symptom deterioration of COPD and CHF inter(re)act.

Aim: Assess the interplay between COPD and CHF deterioration at group and individual level.

Methods: Total daily COPD (0-7) and CHF (0-6) symptom scores, based on increased symptoms reported in 1-year daily diaries (ERJ 2019 54:1802134), were used to assess the COPD-CHF interplay at group and individual level using two mixed models.

Results: 33 patients (72±8 years, 24 men (73%)) were included.

Model 1 shows that, at group level, increased CHF symptom score predicts next day’s COPD symptoms (p=0.02). This was not consistently observed at individual level due to the large variation in the direction and strength of the individual-level associations (Fig 1A).

Model 2 shows that, at group level, increased COPD symptom score predicts next day’s CHF symptoms (p<0.001). Less variation was observed in the direction of the model 2 individual-level associations, still, they differed in strength from no association to strong positive associations (Fig 1B).

Conclusions: At group level, CHF deterioration predicts an increase in next day’s COPD symptom score as well as vice versa. Yet, at individual level, only the group-level conclusion of model 2 holds. Increased COPD symptoms thus consistently predict deterioration of CHF the next day within individual patients.

Original languageEnglish
Article numberPA3021
Number of pages3
JournalEuropean respiratory journal
Volume64
Issue numberSuppl. 68
DOIs
Publication statusPublished - Sept 2024
EventERS international congress 2024 - Vienna, Austria
Duration: 7 Sept 202411 Sept 2024

Keywords

  • NLA

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