Often, knee injury and disorders are caused by or lead to abnormal biomechanical loading patterns in the knee joint menisci. Quantitative information on in vivo loading patterns is therefore in high demand to evaluate therapy and prevent further damage. T1ρ and T2 in meniscus were shown to increase upon application of compressive load, although the mechanisms leading to changes remain unclear. In this work we apply compressive load on the meniscus of volunteers and one cadaver and show that compression-induced internal fiber reorganization may manifest as the magic angle effect, which may be responsible for load-induced T2 and T1ρ increases.
|Publication status||Published - 22 Apr 2017|
|Event||25th ISMRM Annual Meeting & Exhibition 2017 - Hawai'i Convention Center, Honolulu, United States|
Duration: 22 Apr 2017 → 27 Apr 2017
Conference number: 25
|Conference||25th ISMRM Annual Meeting & Exhibition 2017|
|Abbreviated title||ISMRM 2017|
|Period||22/04/17 → 27/04/17|