The pH-static enzyme sensor: An ISFET-based enzyme sensor, insensitive to the buffer capacity of the sample

Bart H. van der Schoot, Piet Bergveld

    Research output: Contribution to journalArticleAcademic

    31 Citations (Scopus)
    63 Downloads (Pure)

    Abstract

    An ISFET-based urea sensor is combined with a noble-metal electrode which provides continuous coulometric titration of the products of the enzymatic reaction. The sensor thus becomes independent of the buffer capacity of the sample; and because the enzyme is operating at a constant pH, the linear response range is expanded.
    Original languageEnglish
    Pages (from-to)157-160
    JournalAnalytica chimica acta
    Volume199
    DOIs
    Publication statusPublished - 1987

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