The predictive value of pain event-related potentials for the clinical experience of pain

Helen Vossen, Jim van Os, Hermanus J. Hermens, Richel Lousberg

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

Event-related potentials (ERPs) have been found to be related to subjective experience of experimental pain. But how are they related to the subjective experience of clinical pain? The current study investigated the predictive value of the pain ERP for the subjective experience of clinical pain. Event-related potentials in response to experimental pain were measured in 75 chronic low back pain sufferers. In addition, a two-week registration to note the amount of pain they experienced in daily life was done. The results demonstrate that the N2-component at Cz and C4 of the pain ERP (contralateral to the side of the stimulation) were significant predictors of clinical pain, and even stronger predictors than the accompanying subjective ratings of experimental pain. Thus, it seems promising to use event-related potentials as a more objective measure to make predictions about a person's likely pain experience in daily life.
Original languageUndefined
Pages (from-to)1-10
Number of pages10
JournalJournal of integrative neuroscience
Volume9
Issue number1
DOIs
Publication statusPublished - 2010

Keywords

  • predictive value
  • EWI-18952
  • BSS-Biomechatronics and rehabilitation technology
  • Chronic pain
  • METIS-277456
  • IR-75114
  • Event related potentials

Cite this

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title = "The predictive value of pain event-related potentials for the clinical experience of pain",
abstract = "Event-related potentials (ERPs) have been found to be related to subjective experience of experimental pain. But how are they related to the subjective experience of clinical pain? The current study investigated the predictive value of the pain ERP for the subjective experience of clinical pain. Event-related potentials in response to experimental pain were measured in 75 chronic low back pain sufferers. In addition, a two-week registration to note the amount of pain they experienced in daily life was done. The results demonstrate that the N2-component at Cz and C4 of the pain ERP (contralateral to the side of the stimulation) were significant predictors of clinical pain, and even stronger predictors than the accompanying subjective ratings of experimental pain. Thus, it seems promising to use event-related potentials as a more objective measure to make predictions about a person's likely pain experience in daily life.",
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The predictive value of pain event-related potentials for the clinical experience of pain. / Vossen, Helen; van Os, Jim; Hermens, Hermanus J.; Lousberg, Richel.

In: Journal of integrative neuroscience, Vol. 9, No. 1, 2010, p. 1-10.

Research output: Contribution to journalArticleAcademicpeer-review

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AU - Vossen, Helen

AU - van Os, Jim

AU - Hermens, Hermanus J.

AU - Lousberg, Richel

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AB - Event-related potentials (ERPs) have been found to be related to subjective experience of experimental pain. But how are they related to the subjective experience of clinical pain? The current study investigated the predictive value of the pain ERP for the subjective experience of clinical pain. Event-related potentials in response to experimental pain were measured in 75 chronic low back pain sufferers. In addition, a two-week registration to note the amount of pain they experienced in daily life was done. The results demonstrate that the N2-component at Cz and C4 of the pain ERP (contralateral to the side of the stimulation) were significant predictors of clinical pain, and even stronger predictors than the accompanying subjective ratings of experimental pain. Thus, it seems promising to use event-related potentials as a more objective measure to make predictions about a person's likely pain experience in daily life.

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