The predictive value of pain event-related potentials for the clinical experience of pain

Helen Vossen; Jim van Os; Hermanus J. Hermens; Richel Lousberg

doi:10.1142/S0219635210002354

The predictive value of pain event-related potentials for the clinical experience of pain

Helen Vossen, Jim van Os, Hermanus J. Hermens, Richel Lousberg

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Event-related potentials (ERPs) have been found to be related to subjective experience of experimental pain. But how are they related to the subjective experience of clinical pain? The current study investigated the predictive value of the pain ERP for the subjective experience of clinical pain. Event-related potentials in response to experimental pain were measured in 75 chronic low back pain sufferers. In addition, a two-week registration to note the amount of pain they experienced in daily life was done. The results demonstrate that the N2-component at Cz and C4 of the pain ERP (contralateral to the side of the stimulation) were significant predictors of clinical pain, and even stronger predictors than the accompanying subjective ratings of experimental pain. Thus, it seems promising to use event-related potentials as a more objective measure to make predictions about a person's likely pain experience in daily life.

Original language	Undefined
Pages (from-to)	1-10
Number of pages	10
Journal	Journal of integrative neuroscience
Volume	9
Issue number	1
DOIs	https://doi.org/10.1142/S0219635210002354
Publication status	Published - 2010

Keywords

predictive value
EWI-18952
BSS-Biomechatronics and rehabilitation technology
Chronic pain
METIS-277456
IR-75114
Event related potentials

Access to Document

10.1142/S0219635210002354

Cite this

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abstract = "Event-related potentials (ERPs) have been found to be related to subjective experience of experimental pain. But how are they related to the subjective experience of clinical pain? The current study investigated the predictive value of the pain ERP for the subjective experience of clinical pain. Event-related potentials in response to experimental pain were measured in 75 chronic low back pain sufferers. In addition, a two-week registration to note the amount of pain they experienced in daily life was done. The results demonstrate that the N2-component at Cz and C4 of the pain ERP (contralateral to the side of the stimulation) were significant predictors of clinical pain, and even stronger predictors than the accompanying subjective ratings of experimental pain. Thus, it seems promising to use event-related potentials as a more objective measure to make predictions about a person's likely pain experience in daily life.",

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AU - van Os, Jim

AU - Hermens, Hermanus J.

AU - Lousberg, Richel

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