TY - JOUR
T1 - The relation between atherosclerosis and the occurrence of postoperative delirium in vascular surgery patients
AU - Pol, Robert A.
AU - Van Leeuwen, Barbara L.
AU - Reijnen, Michel M.P.J.
AU - Zeebregts, Clark J.
PY - 2012/4/1
Y1 - 2012/4/1
N2 - Old and frail patients undergoing vascular surgery seem at great risk of developing postoperative delirium (POD). The aim of this review was to identify risk factors for the development of POD in vascular surgery patients. Different aetiological factors have been identified, such as increased age, excessive blood transfusion, preoperative cognitive impairment and depression. Mounting evidence supports a role for inflammation and tobacco exposure in the development of POD. Vascular surgery patients differ from the general surgical population because they suffer from both loco-regional and systemic atherosclerosis. Although current scientific evidence cannot fully link both entities, evidence is growing that suggests a relationship between systemic and cerebrovascular atherosclerosis and the development of POD.
AB - Old and frail patients undergoing vascular surgery seem at great risk of developing postoperative delirium (POD). The aim of this review was to identify risk factors for the development of POD in vascular surgery patients. Different aetiological factors have been identified, such as increased age, excessive blood transfusion, preoperative cognitive impairment and depression. Mounting evidence supports a role for inflammation and tobacco exposure in the development of POD. Vascular surgery patients differ from the general surgical population because they suffer from both loco-regional and systemic atherosclerosis. Although current scientific evidence cannot fully link both entities, evidence is growing that suggests a relationship between systemic and cerebrovascular atherosclerosis and the development of POD.
KW - atherosclerosis
KW - cognitive decline
KW - postoperative delirium
KW - vascular surgery
UR - http://www.scopus.com/inward/record.url?scp=84861834613&partnerID=8YFLogxK
U2 - 10.1177/1358863X11429723
DO - 10.1177/1358863X11429723
M3 - Article
C2 - 22302037
AN - SCOPUS:84861834613
SN - 1358-863X
VL - 17
SP - 116
EP - 122
JO - Vascular Medicine (United Kingdom)
JF - Vascular Medicine (United Kingdom)
IS - 2
ER -