The role of 18F-FDG-PET/CT in the management of patients with high-risk breast cancer: case series and guideline comparison

Ben Bulten, M.J. de Haas, H.J. Bloemendal, A.J. van Overbeeke, J.P. Esser, H.J. Baarslag, Lioe-Fee de Geus-Oei, J.M.H. de Klerk

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Abstract

Objectives: In grade III-IV breast cancer, dissemination of disease needs to be assessed. Until now this was done by conventional imaging (liver ultrasonography, chest X-ray and bone scintigraphy), but evidence favoring the use of FDG-PET/CT is accumulating. Methods: Patients with high-risk breast cancer, who had received conventional imaging and FDG-PET/CT, were included. Patients were staged and assigned a treatment after 1) conventional imaging and 2) FDG-PET/CT, both by a multidisciplinary oncology team. Equivocal FDG-PET/CT findings were histologically confirmed. Results: 16 patients were included (mean age 59 years). TNM-stage changed in 5 patients (31%) after FDG-PET/CT. In 3 patients (19%) unknown distant metastases were detected by FDG-PET/CT. An adjustment of treatment took place in 4 patients (25%). Conclusions: Our case series emphasizes the role of FDG-PET/CT in the staging of high-risk breast carcinoma, especially in the assessment of distant metastases. We suggest replacing conventional imaging with FDG-PET/CT.
Original languageUndefined
Pages (from-to)35-41
JournalAdvances in molecular imaging
Volume4
Issue number3
DOIs
Publication statusPublished - 2014

Keywords

  • IR-94983
  • METIS-306770

Cite this

Bulten, B., de Haas, M. J., Bloemendal, H. J., van Overbeeke, A. J., Esser, J. P., Baarslag, H. J., ... de Klerk, J. M. H. (2014). The role of 18F-FDG-PET/CT in the management of patients with high-risk breast cancer: case series and guideline comparison. Advances in molecular imaging, 4(3), 35-41. https://doi.org/10.4236/ami.2014.43005