The traveling heads: multicenter brain imaging at 7 Tesla

M.N. Voelker, O. Kraff, O. Kraff, D. Brenner, A. Wollrab, O. Weinberger, M.C. Berger, S. Robinson, W. Bogner, C. Wiggins, R. Trampel, T. Stöcker, T. Niendorf, H.H. Quick, David Gordon Norris, M.E. Ladd, O. Speck

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)


Objective This study evaluates the inter-site and intra-site reproducibility of 7 Tesla brain imaging and compares it to literature values for other field strengths. Materials and methods The same two subjects were imaged at eight different 7 T sites. MP2RAGE, TSE, TOF, SWI, EPI as well as B1 and B0 field maps were analyzed quantitatively to assess inter-site reproducibility. Intra-site reproducibility was measured with rescans at three sites. Results Quantitative measures of MP2RAGE scans showed high agreement. Inter-site and intra-site reproducibility errors were comparable to 1.5 and 3 T. Other sequences also showed high reproducibility between the sites, but differences were also revealed. The different RF coils used were the main source for systematic differences between the sites. Conclusion Our results show for the first time that multi-center brain imaging studies of the supratentorial brain can be performed at 7 T with high reproducibility and similar reliability as at 3T. This study develops the basis for future large-scale 7 T multi-site studies
Original languageEnglish
Pages (from-to)399-415
Number of pages16
JournalMagnetic resonance materials in physics, biology and medicine
Issue number3
Publication statusPublished - 2016


  • METIS-317779
  • IR-101136


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