The traveling heads: multicenter brain imaging at 7 Tesla

Maximilian N. Voelker*, Oliver Kraff, Daniel Brenner, Astrid Wollrab, Oliver Weinberger, Moritz C. Berger, Simon Robinson, Wolfgang Bogner, Christopher Wiggins, Robert Trampel, Tony Stöcker, Thoralf Niendorf, Harald H. Quick, David G. Norris, Mark E. Ladd, Oliver Speck

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

20 Citations (Scopus)


Objective: This study evaluates the inter-site and intra-site reproducibility of 7 Tesla brain imaging and compares it to literature values for other field strengths.

Materials and methods: The same two subjects were imaged at eight different 7 T sites. MP2RAGE, TSE, TOF, SWI, EPI as well as B1 and B0 field maps were analyzed quantitatively to assess inter-site reproducibility. Intra-site reproducibility was measured with rescans at three sites.

Results: Quantitative measures of MP2RAGE scans showed high agreement. Inter-site and intra-site reproducibility errors were comparable to 1.5 and 3 T. Other sequences also showed high reproducibility between the sites, but differences were also revealed. The different RF coils used were the main source for systematic differences between the sites.

Conclusion: Our results show for the first time that multi-center brain imaging studies of the supratentorial brain can be performed at 7 T with high reproducibility and similar reliability as at 3T. This study develops the basis for future large-scale 7 T multi-site studies.

Original languageEnglish
Pages (from-to)399-415
Number of pages17
JournalMagnetic resonance materials in physics, biology and medicine
Issue number3
Publication statusPublished - 1 Jun 2016
Externally publishedYes


  • Magnetic resonance imaging (MRI)
  • Multi-center
  • Neuroimaging
  • Ultrahigh field
  • n/a OA procedure


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