TY - GEN
T1 - The Twente Photoacoustic Mammoscope 2
T2 - Photons Plus Ultrasound: Imaging and Sensing 2019
AU - Schoustra, Sjoukje M.
AU - Huijink, Roeland
AU - Alink, Laurens
AU - op 't Root, Tim J.P.M.
AU - Sprünken, Daan
AU - Piras, Daniele
AU - Muller Kobold, Wouter F.
AU - Klazen, Caroline A.H.
AU - van der Schaaf, Margreet C.
AU - van den Engh, Frank M.
AU - Steenbergen, Wiendelt
AU - Manohar, Srirang
PY - 2019/2/27
Y1 - 2019/2/27
N2 - We present the Twente Photoacoustic Mammoscope 2 (PAM 2) based on a 3D tomographic geometry. A functional optical contrast map of breast vascularization can be obtained in a noninvasive, radiation-free and painless manner. A woman lies prone on a bed with one breast pendant in an imaging tank with water, where 12 curved ultrasound arrays are mounted. Each array extends from chest wall towards the nipple following the contour of the pendant breast, and carries 32 detector elements. The detectors' center frequency is 1 MHz. The breast is illuminated from multiple directions: the ventral side of the breast from the bottom and the areas close to the chest wall from the sides. The excitation wavelengths are 755 nm and 1064 nm. By rotating the imaging tank in between measurements, multiple projections can be obtained, providing a 3D image of the breast after reconstruction by means of a filtered backprojection. So far, breasts of healthy volunteers were imaged. Three-dimensional images of the breast contour, the nipple and blood vessel networks within the breast could be observed with high contrast and unprecedented detail.
AB - We present the Twente Photoacoustic Mammoscope 2 (PAM 2) based on a 3D tomographic geometry. A functional optical contrast map of breast vascularization can be obtained in a noninvasive, radiation-free and painless manner. A woman lies prone on a bed with one breast pendant in an imaging tank with water, where 12 curved ultrasound arrays are mounted. Each array extends from chest wall towards the nipple following the contour of the pendant breast, and carries 32 detector elements. The detectors' center frequency is 1 MHz. The breast is illuminated from multiple directions: the ventral side of the breast from the bottom and the areas close to the chest wall from the sides. The excitation wavelengths are 755 nm and 1064 nm. By rotating the imaging tank in between measurements, multiple projections can be obtained, providing a 3D image of the breast after reconstruction by means of a filtered backprojection. So far, breasts of healthy volunteers were imaged. Three-dimensional images of the breast contour, the nipple and blood vessel networks within the breast could be observed with high contrast and unprecedented detail.
KW - Breast cancer
KW - Breast imaging
KW - Breast vascularization
KW - Photoacoustic imaging
KW - Tomography
UR - http://www.scopus.com/inward/record.url?scp=85065443136&partnerID=8YFLogxK
U2 - 10.1117/12.2507448
DO - 10.1117/12.2507448
M3 - Conference contribution
AN - SCOPUS:85065443136
VL - 10878
T3 - Progress in Biomedical Optics and Imaging
BT - Photons Plus Ultrasound
A2 - Wang, Lihong V.
A2 - Oraevsky, Alexander A.
PB - SPIE
CY - Bellingham, WA
Y2 - 2 February 2019 through 7 February 2019
ER -