The Twente Photoacoustic Mammoscope: system overview and performance

Srirang Manohar; A. Kharine; Johannes C.G. van Hespen; Johan C.G. van Hespen; Wiendelt Steenbergen; Ton van Leeuwen

doi:10.1088/0031-9155/50/11/007

The Twente Photoacoustic Mammoscope: system overview and performance

Srirang Manohar, A. Kharine, Johannes C.G. van Hespen, Johan C.G. van Hespen, Wiendelt Steenbergen, Ton van Leeuwen

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

We present PAM, the Photoacoustic Mammoscope developed at the University of Twente, intended for initial retrospective clinical studies on subjects with breast tumours. A parallel plate geometry has been adopted and the breast will be gently compressed between a glass plate and a flat ultrasound detector matrix. Pulsed light (5 ns) from an Nd:YAG laser will impinge the breast through the glass plate in regions of interest; an appropriate number of the 590 elements of the detector matrix will be activated in succession to record photoacoustic signals. Three-dimensional image reconstruction employs a delay-and-sum beamforming algorithm. We discuss various instrumental aspects and the proposed imaging protocol. Performance studies of the ultrasound detector are presented in terms of sensitivity, frequency response and resolution. Details of the patient–instrument interface are provided. Finally some imaging results on well-characterized breast tissue phantoms with embedded tumour simulating inserts are shown.

Original language	Undefined
Pages (from-to)	2543-2557
Number of pages	15
Journal	Physics in medicine and biology
Volume	50
Issue number	11
DOIs	https://doi.org/10.1088/0031-9155/50/11/007
Publication status	Published - 2005

Keywords

IR-58699
METIS-224137

Access to Document

10.1088/0031-9155/50/11/007

Cite this

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title = "The Twente Photoacoustic Mammoscope: system overview and performance",

abstract = "We present PAM, the Photoacoustic Mammoscope developed at the University of Twente, intended for initial retrospective clinical studies on subjects with breast tumours. A parallel plate geometry has been adopted and the breast will be gently compressed between a glass plate and a flat ultrasound detector matrix. Pulsed light (5 ns) from an Nd:YAG laser will impinge the breast through the glass plate in regions of interest; an appropriate number of the 590 elements of the detector matrix will be activated in succession to record photoacoustic signals. Three-dimensional image reconstruction employs a delay-and-sum beamforming algorithm. We discuss various instrumental aspects and the proposed imaging protocol. Performance studies of the ultrasound detector are presented in terms of sensitivity, frequency response and resolution. Details of the patient–instrument interface are provided. Finally some imaging results on well-characterized breast tissue phantoms with embedded tumour simulating inserts are shown.",

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T1 - The Twente Photoacoustic Mammoscope: system overview and performance

AU - Manohar, Srirang

AU - Kharine, A.

AU - van Hespen, Johannes C.G.

AU - van Hespen, Johan C.G.

AU - Steenbergen, Wiendelt

AU - van Leeuwen, Ton

PY - 2005

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AB - We present PAM, the Photoacoustic Mammoscope developed at the University of Twente, intended for initial retrospective clinical studies on subjects with breast tumours. A parallel plate geometry has been adopted and the breast will be gently compressed between a glass plate and a flat ultrasound detector matrix. Pulsed light (5 ns) from an Nd:YAG laser will impinge the breast through the glass plate in regions of interest; an appropriate number of the 590 elements of the detector matrix will be activated in succession to record photoacoustic signals. Three-dimensional image reconstruction employs a delay-and-sum beamforming algorithm. We discuss various instrumental aspects and the proposed imaging protocol. Performance studies of the ultrasound detector are presented in terms of sensitivity, frequency response and resolution. Details of the patient–instrument interface are provided. Finally some imaging results on well-characterized breast tissue phantoms with embedded tumour simulating inserts are shown.

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KW - METIS-224137

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