Therapy using perturbation and effect of physiological systems

L. Kornet (Inventor), Petrus H. Veltink (Inventor), J.E. Burnes (Inventor), M.R.S. Hill (Inventor), R.N.M. Cornelussen (Inventor), Simone Cornelia Maria Anna Ordelman (Inventor), H.P.J. Buschman (Inventor)

    Research output: Patent

    9 Downloads (Pure)

    Abstract

    The disclosure herein relates generally to methods and devices for use in treating a patient by utilizing a response index associated with a selected organ. The selected organ may be assessed by comparing the response index to psychological parameters monitored in response to one or more perturbations. For example, the status of the selected organ may be assessed by comparing the relationship between one or more perturbations (e.g., electrical stimulation of the efferent vagus nerve) and one or more effects associated with the one or more perturbations (e.g., electrical activity effect of the vagus nerve, effect on the sympathetic efferent pathways, etc.). Information derived by the comparisons using the response index may be used to initiate or adjust therapy delivered by medical devices such as an implantable medical device (IMD) (e.g., a pacemaker (PM), an implantable cardioverter defibrillator (ICD), neuromodulation system, etc.).
    Original languageUndefined
    Patent number61/329,374
    Priority date29/04/10
    Publication statusSubmitted - 29 Apr 2010

    Keywords

    • BSS-Biomechatronics and rehabilitation technology
    • EWI-17863
    • Vagus Nerve
    • IR-76677
    • response index
    • METIS-276706
    • Pertubations

    Cite this

    Kornet, L., Veltink, P. H., Burnes, J. E., Hill, M. R. S., Cornelussen, R. N. M., Ordelman, S. C. M. A., & Buschman, H. P. J. (2010). Therapy using perturbation and effect of physiological systems. Manuscript submitted for publication. (Patent No. 61/329,374).
    Kornet, L. (Inventor) ; Veltink, Petrus H. (Inventor) ; Burnes, J.E. (Inventor) ; Hill, M.R.S. (Inventor) ; Cornelussen, R.N.M. (Inventor) ; Ordelman, Simone Cornelia Maria Anna (Inventor) ; Buschman, H.P.J. (Inventor). / Therapy using perturbation and effect of physiological systems. Patent No.: 61/329,374.
    @misc{20b4a9074b0f496ba2cd80c5029f6782,
    title = "Therapy using perturbation and effect of physiological systems",
    abstract = "The disclosure herein relates generally to methods and devices for use in treating a patient by utilizing a response index associated with a selected organ. The selected organ may be assessed by comparing the response index to psychological parameters monitored in response to one or more perturbations. For example, the status of the selected organ may be assessed by comparing the relationship between one or more perturbations (e.g., electrical stimulation of the efferent vagus nerve) and one or more effects associated with the one or more perturbations (e.g., electrical activity effect of the vagus nerve, effect on the sympathetic efferent pathways, etc.). Information derived by the comparisons using the response index may be used to initiate or adjust therapy delivered by medical devices such as an implantable medical device (IMD) (e.g., a pacemaker (PM), an implantable cardioverter defibrillator (ICD), neuromodulation system, etc.).",
    keywords = "BSS-Biomechatronics and rehabilitation technology, EWI-17863, Vagus Nerve, IR-76677, response index, METIS-276706, Pertubations",
    author = "L. Kornet and Veltink, {Petrus H.} and J.E. Burnes and M.R.S. Hill and R.N.M. Cornelussen and Ordelman, {Simone Cornelia Maria Anna} and H.P.J. Buschman",
    year = "2010",
    month = "4",
    day = "29",
    language = "Undefined",
    type = "Patent",
    note = "61/329,374",

    }

    Kornet, L, Veltink, PH, Burnes, JE, Hill, MRS, Cornelussen, RNM, Ordelman, SCMA & Buschman, HPJ 2010, Therapy using perturbation and effect of physiological systems, Patent No. 61/329,374.

    Therapy using perturbation and effect of physiological systems. / Kornet, L. (Inventor); Veltink, Petrus H. (Inventor); Burnes, J.E. (Inventor); Hill, M.R.S. (Inventor); Cornelussen, R.N.M. (Inventor); Ordelman, Simone Cornelia Maria Anna (Inventor); Buschman, H.P.J. (Inventor).

    Patent No.: 61/329,374.

    Research output: Patent

    TY - PAT

    T1 - Therapy using perturbation and effect of physiological systems

    AU - Kornet, L.

    AU - Veltink, Petrus H.

    AU - Burnes, J.E.

    AU - Hill, M.R.S.

    AU - Cornelussen, R.N.M.

    AU - Ordelman, Simone Cornelia Maria Anna

    AU - Buschman, H.P.J.

    PY - 2010/4/29

    Y1 - 2010/4/29

    N2 - The disclosure herein relates generally to methods and devices for use in treating a patient by utilizing a response index associated with a selected organ. The selected organ may be assessed by comparing the response index to psychological parameters monitored in response to one or more perturbations. For example, the status of the selected organ may be assessed by comparing the relationship between one or more perturbations (e.g., electrical stimulation of the efferent vagus nerve) and one or more effects associated with the one or more perturbations (e.g., electrical activity effect of the vagus nerve, effect on the sympathetic efferent pathways, etc.). Information derived by the comparisons using the response index may be used to initiate or adjust therapy delivered by medical devices such as an implantable medical device (IMD) (e.g., a pacemaker (PM), an implantable cardioverter defibrillator (ICD), neuromodulation system, etc.).

    AB - The disclosure herein relates generally to methods and devices for use in treating a patient by utilizing a response index associated with a selected organ. The selected organ may be assessed by comparing the response index to psychological parameters monitored in response to one or more perturbations. For example, the status of the selected organ may be assessed by comparing the relationship between one or more perturbations (e.g., electrical stimulation of the efferent vagus nerve) and one or more effects associated with the one or more perturbations (e.g., electrical activity effect of the vagus nerve, effect on the sympathetic efferent pathways, etc.). Information derived by the comparisons using the response index may be used to initiate or adjust therapy delivered by medical devices such as an implantable medical device (IMD) (e.g., a pacemaker (PM), an implantable cardioverter defibrillator (ICD), neuromodulation system, etc.).

    KW - BSS-Biomechatronics and rehabilitation technology

    KW - EWI-17863

    KW - Vagus Nerve

    KW - IR-76677

    KW - response index

    KW - METIS-276706

    KW - Pertubations

    M3 - Patent

    M1 - 61/329,374

    ER -

    Kornet L, Veltink PH, Burnes JE, Hill MRS, Cornelussen RNM, Ordelman SCMA et al, inventors. Therapy using perturbation and effect of physiological systems. 61/329,374. 2010 Apr 29.