Thermoreversible gelation behaviour of PTMC-PEG-PTMC triblock copolymers

E. Bat, W.E. Hennink (Editor), Dirk W. Grijpma, J. Feijen (Editor), A.P. Sam (Editor), Jan Feijen

Research output: Contribution to conferencePaperAcademic

Abstract

Triblock copolymers of trimethylene carbonate (TMC) and polyethylene glycol (PEG) were synthesized. Their gelation behaviour in water and the properties of the gels were investigated by particle size measurements, the vial tilting method, and dynamic rheology. As the temperature was decreased, the average particle size increased and sol-to-gel transition was observed. The storage modulus of these thermoreversible gels ranged from 220 Pa to 4700 Pa depending on the composition and concentration of the copolymer.
Original languageUndefined
Pagese37-e39
DOIs
Publication statusPublished - 2 Apr 2008
Event10th European Symposium on Controlled Drug Delivery, ESCDD 2008 - Noordwijk aan Zee, Netherlands
Duration: 2 Apr 20084 Apr 2008
Conference number: 10

Conference

Conference10th European Symposium on Controlled Drug Delivery, ESCDD 2008
Abbreviated titleESCDD
CountryNetherlands
CityNoordwijk aan Zee
Period2/04/084/04/08

Keywords

  • METIS-254011
  • IR-68967

Cite this

Bat, E., Hennink, W. E. (Ed.), Grijpma, D. W., Feijen, J. (Ed.), Sam, A. P. (Ed.), & Feijen, J. (2008). Thermoreversible gelation behaviour of PTMC-PEG-PTMC triblock copolymers. e37-e39. Paper presented at 10th European Symposium on Controlled Drug Delivery, ESCDD 2008, Noordwijk aan Zee, Netherlands. https://doi.org/10.1016/j.jconrel.2008.09.024
Bat, E. ; Hennink, W.E. (Editor) ; Grijpma, Dirk W. ; Feijen, J. (Editor) ; Sam, A.P. (Editor) ; Feijen, Jan. / Thermoreversible gelation behaviour of PTMC-PEG-PTMC triblock copolymers. Paper presented at 10th European Symposium on Controlled Drug Delivery, ESCDD 2008, Noordwijk aan Zee, Netherlands.
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abstract = "Triblock copolymers of trimethylene carbonate (TMC) and polyethylene glycol (PEG) were synthesized. Their gelation behaviour in water and the properties of the gels were investigated by particle size measurements, the vial tilting method, and dynamic rheology. As the temperature was decreased, the average particle size increased and sol-to-gel transition was observed. The storage modulus of these thermoreversible gels ranged from 220 Pa to 4700 Pa depending on the composition and concentration of the copolymer.",
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Bat, E, Hennink, WE (ed.), Grijpma, DW, Feijen, J (ed.), Sam, AP (ed.) & Feijen, J 2008, 'Thermoreversible gelation behaviour of PTMC-PEG-PTMC triblock copolymers' Paper presented at 10th European Symposium on Controlled Drug Delivery, ESCDD 2008, Noordwijk aan Zee, Netherlands, 2/04/08 - 4/04/08, pp. e37-e39. https://doi.org/10.1016/j.jconrel.2008.09.024

Thermoreversible gelation behaviour of PTMC-PEG-PTMC triblock copolymers. / Bat, E.; Hennink, W.E. (Editor); Grijpma, Dirk W.; Feijen, J. (Editor); Sam, A.P. (Editor); Feijen, Jan.

2008. e37-e39 Paper presented at 10th European Symposium on Controlled Drug Delivery, ESCDD 2008, Noordwijk aan Zee, Netherlands.

Research output: Contribution to conferencePaperAcademic

TY - CONF

T1 - Thermoreversible gelation behaviour of PTMC-PEG-PTMC triblock copolymers

AU - Bat, E.

AU - Grijpma, Dirk W.

AU - Feijen, Jan

A2 - Hennink, W.E.

A2 - Feijen, J.

A2 - Sam, A.P.

PY - 2008/4/2

Y1 - 2008/4/2

N2 - Triblock copolymers of trimethylene carbonate (TMC) and polyethylene glycol (PEG) were synthesized. Their gelation behaviour in water and the properties of the gels were investigated by particle size measurements, the vial tilting method, and dynamic rheology. As the temperature was decreased, the average particle size increased and sol-to-gel transition was observed. The storage modulus of these thermoreversible gels ranged from 220 Pa to 4700 Pa depending on the composition and concentration of the copolymer.

AB - Triblock copolymers of trimethylene carbonate (TMC) and polyethylene glycol (PEG) were synthesized. Their gelation behaviour in water and the properties of the gels were investigated by particle size measurements, the vial tilting method, and dynamic rheology. As the temperature was decreased, the average particle size increased and sol-to-gel transition was observed. The storage modulus of these thermoreversible gels ranged from 220 Pa to 4700 Pa depending on the composition and concentration of the copolymer.

KW - METIS-254011

KW - IR-68967

U2 - 10.1016/j.jconrel.2008.09.024

DO - 10.1016/j.jconrel.2008.09.024

M3 - Paper

SP - e37-e39

ER -

Bat E, Hennink WE, (ed.), Grijpma DW, Feijen J, (ed.), Sam AP, (ed.), Feijen J. Thermoreversible gelation behaviour of PTMC-PEG-PTMC triblock copolymers. 2008. Paper presented at 10th European Symposium on Controlled Drug Delivery, ESCDD 2008, Noordwijk aan Zee, Netherlands. https://doi.org/10.1016/j.jconrel.2008.09.024