TY - JOUR
T1 - Third-generation amperometric biosensor for glucose
T2 - Polypyrrole deposited within a matrix of uniform latex particles as mediator
AU - Koopal, Cornelis G.J.
AU - Feiters, Martinus C.
AU - Nolte, Roeland J.M.
AU - de Ruiter, Barteld
AU - Schasfoort, Richard B.M.
PY - 1992/1/1
Y1 - 1992/1/1
N2 - Uniform latex particles and agarose gels are utilized to create porous membranes in which polypyrrole is electrochemically synthesized. Within the pores of these modified membranes glucose oxidase can be adsorbed irreversibly while its catalytic activity is retained. A glucose sensor which has a considerable lifetime under continuous use is constructed from the enzyme membrane. With this sensor glucose can be measured amperometrically in the concentration range 1-60 mM. The sensor response is independent of oxygen concentration.
AB - Uniform latex particles and agarose gels are utilized to create porous membranes in which polypyrrole is electrochemically synthesized. Within the pores of these modified membranes glucose oxidase can be adsorbed irreversibly while its catalytic activity is retained. A glucose sensor which has a considerable lifetime under continuous use is constructed from the enzyme membrane. With this sensor glucose can be measured amperometrically in the concentration range 1-60 mM. The sensor response is independent of oxygen concentration.
U2 - 10.1016/0302-4598(92)80064-N
DO - 10.1016/0302-4598(92)80064-N
M3 - Article
AN - SCOPUS:0001418818
SN - 0302-4598
VL - 29
SP - 159
EP - 175
JO - Bioelectrochemistry and bioenergetics
JF - Bioelectrochemistry and bioenergetics
IS - 2
ER -