Time domain algorithm for accelerated determiniation of the first order moment of photo current fluctuations in high speed laser Doppler perfusion imaging

Matthijs Draijer, Erwin Hondebrink, Ton van Leeuwen, Wiendelt Steenbergen

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)
88 Downloads (Pure)


Advances in optical array sensor technology allow for the real time acquisition of dynamic laser speckle patterns generated by tissue perfusion, which, in principle, allows for real time laser Doppler perfusion imaging (LDPI). Exploitation of these developments is enhanced with the introduction of faster algorithms to transform photo currents into perfusion estimates using the first moment of the power spectrum. A time domain (TD) algorithm is presented for determining the first-order spectral moment. Experiments are performed to compare this algorithm with the widely used Fast Fourier Transform (FFT). This study shows that the TD-algorithm is twice as fast as the FFT-algorithm without loss of accuracy. Compared to FFT, the TD-algorithm is efficient in terms of processor time, memory usage and data transport
Original languageUndefined
Pages (from-to)1103-1109
Number of pages7
JournalMedical & biological engineering & computing
Issue number10
Publication statusPublished - 2009


  • IR-76389
  • METIS-259362

Cite this